DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sprt and Pdzd3

DIOPT Version :9

Sequence 1:	NP_610683.1	Gene:	sprt / 246397	FlyBaseID:	FBgn0082585	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_001178925.1	Gene:	Pdzd3 / 500986	RGDID:	1559807	Length:	498	Species:	Rattus norvegicus

Alignment Length:	138	Identity:	30/138 - (21%)
Similarity:	52/138 - (37%)	Gaps:	30/138 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 DNIDIRIRQAELEYALGREELQMLSIVEEARALQAR-----LEKSKPEAQTLYNIISSGVSLSLH 220
            |.:.:.:...|:|....:..:.:.:.:.|..||.|:     :||. |:          |....|.
  Rat   225 DRVTLLVAGPEVEEQCHQLGMPLAAPLAEGWALPAKPRCLNIEKG-PQ----------GFGFLLR 278

  Fly   221 AVHATSGR-----WAVQQRTDQPGFYVEWALEGDGLYKGDRILEINGRLVTGKSKEELQKQVGNS 280
            ......||     |.|     .||...:.|    |:..|||::.:.|..:.|...||...::...
  Rat   279 EEKGPDGRLGQFLWEV-----DPGLPADKA----GMKAGDRLVAVAGESMDGLGHEETVSRIRAQ 334

  Fly   281 GKCQMVVL 288
            |.|..:|:
  Rat   335 GSCVSLVV 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sprt	NP_610683.1	PDZ	<247..288	CDD:294084	10/40 (25%)
Pdzd3	NP_001178925.1	PDZ_signaling	47..127	CDD:238492
		PDZ_signaling	155..232	CDD:238492	1/6 (17%)
		PDZ	260..345	CDD:214570	23/103 (22%)
		PDZ_signaling	407..472	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900