Protein Alignment sprt and Mhcl

DIOPT Version :9

• Sequence 1: NP_610683.1
• Gene: sprt / 246397
• FlyBaseID: FBgn0082585
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_732109.2
• Gene: Mhcl / 41955
• FlyBaseID: FBgn0026059
• Length: 2194
• Species: Drosophila melanogaster
• Alignment Length: 656
• Identity: 130/656 - (19%)
• Similarity: 243/656 - (37%)
• Gaps: 196/656 - (29%)

  Fly    81 RSTRSESKELRSAL-QDREAVIQNLRIQLCLGKLPRPTGPPLDESEKPAAEQKLNRLKTEAENKR 144
            |...:|.:.|:.|: |:|:|..:..|.:..|            ::||...||.|...:.:.|.|.
  Fly  1596 RKFDAECQSLQDAVRQERQAKERYGREKDVL------------QAEKFTLEQTLADTRLDLEFKE 1648

  Fly   145 IKIKNLKSALEKLDI---TDNIDIRIRQA--ELEYALGREELQM------LSIVEEAR-ALQARL 197
            .|:.:|:..||::..   |:....::|::  |.|.....:|.::      :.::|:|: .|:..|
  Fly  1649 EKLASLQRELEEMTFGGGTEEEFAQLRRSKNETERRAKEQEEELDEMAGQIQLLEQAKLRLEMTL 1713

  Fly   198 EKSKPEAQTLYNIISSGVSLSLHAVHATSGRWAVQQRTDQPGFYVEWALEGDGLYKGDRILEI-- 260
            |..:.||                       |...|||.::    :| .:.|:| ||..:.||.
  Fly  1714 ETMRKEA-----------------------RRESQQRDEE----LE-EVRGNG-YKKIKALECQL 1749

  Fly   261 ----NGRLVTGKSKEELQKQVGNSGKCQMVVLRKKSVPIPQKQLDQEKENNMRLQHRI----SYL 317
                ..|.:..:.|.||::::.:......|            ..|.|:..|.:|:..:    :.|
  Fly  1750 ETEHEERTLLLREKHELERRLSSMEDRDRV------------DRDAEEALNQKLRRDLRKYKALL 1802

  Fly   318 EEQVRELQTVKEHHPSQQQQQQQQQQQNPQQNPQQNPQQTSSNQSQHVTSISISSPPSTPPEKPL 382
            ::...:|:.:|...|.:...:|.:.|....::.:....:........:|.
  Fly  1803 KDAQTQLERLKADTPGKTLIRQLRNQLEDAESARSLAMKARQTAEAELTE--------------- 1852

  Fly   383 IFQRGNYITTLVGGKPIELMGDDMASTQTPPGHVTKTLIKENTHIDLRDR--------------- 432
                            ::.|.|:        .|..:...:|..:...|||
  Fly  1853 ----------------VQAMFDE--------SHRARNDAEERANAAHRDRAELQAQIEENEEELG 1893

  Fly   433 -LSHMYSMPSKSLSASKISINSDSAY----MQHHRRD-KERHRDRQHR----ERPRDP----LQQ 483
             |...||...|.|:..:|:: |::.:    |:..|.: ||:..:.|||    |...||    :.:
  Fly  1894 ELMKKYSATVKQLNTEQINV-SEAEFKLNEMEAERNNLKEQVAELQHRLDNVENLGDPSMAMMSK 1957

  Fly   484 QQQLHREHLMS-------THARSVEHLN-HYNGLDRRRDTPRQSESNTLRAR--LPSDMRSVKSL 538
            :.:|..:.|.|       |.||....:| |...|::.::...||:...::|:  :....:|::.:
  Fly  1958 RLELRTKELESRLELEQATRARLEVQVNRHKEALEKLQNEVTQSKMREMQAQDVIKKSQKSLRDM 2022

  Fly   539 DFDSENESKPATETRTTRPTPPKK-------------PLRLSLQRAQSLQTV------------- 577
            ..:....|....|:.|.|....||             .|||:|||...||..
  Fly  2023 REEFHAVSSREQESLTRRKDLEKKVEQMESEGAALKNDLRLALQRIADLQQAMEEEGEEELSESD 2087

  Fly   578 ----ELHPCADIE-RKRP--MKRVHHNNNNNN--KGGESPTGEGQTMLIE--NCSPMHT----AS 627
                .:...:|:| |.||  :||....:.|.:  .||.|.....:|::.|  :.||..|    :|
  Fly  2088 ESLSSVGSISDLEDRLRPVHVKRSSQQSLNGSIGGGGGSVVSSTRTVVFEKDDNSPRITVTSPSS 2152

  Fly   628 LGRHKL 633
            ...|||
  Fly  2153 PHIHKL 2158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sprt	NP_610683.1	PDZ	<247..288	CDD:294084	11/46 (24%)
Mhcl	NP_732109.2	PDZ_signaling	339..426	CDD:238492
		MYSc	556..1317	CDD:214580
		MYSc_Myo18	575..1305	CDD:276837
		GBP_C	<1540..1750	CDD:303769	43/194 (22%)
		COG1340	1565..1833	CDD:224259	58/289 (20%)
		coiled coil	1723..1734	CDD:293879	4/15 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900