Protein Alignment sprt and dysc

DIOPT Version :9

• Sequence 1: NP_610683.1
• Gene: sprt / 246397
• FlyBaseID: FBgn0082585
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001261810.1
• Gene: dysc / 39533
• FlyBaseID: FBgn0264006
• Length: 1254
• Species: Drosophila melanogaster
• Alignment Length: 645
• Identity: 127/645 - (19%)
• Similarity: 200/645 - (31%)
• Gaps: 231/645 - (35%)

  Fly     1 MDTGSVV--SEPISAHHRAFAKQKSASMTILNPKGCGSAVKYSLHSTAETNQETASTTTTSTHCS 63
            |..|.::  |:|.| |::..:.|.|:|   |:|               ...|:.........|.|
  Fly   715 MSAGPILHRSQPAS-HYQTGSNQSSSS---LSP---------------PQQQQQQQQHYQPHHAS 760

  Fly    64 TTGRRRKGGSLGGTLSS---------------RSTRSESKELRSALQDREAVIQNLRIQLCLGKL 113
            .    |..|.:||.:.|               |.|:...::.....:.|..
  Fly   761 L----RHLGGIGGNVGSGRHHHHPLGPSQLKFRQTKDNQQQEYGCDEHRTR-------------- 807

  Fly   114 PRPTGPPLDESEKPAAEQKL-NRLKTEAENKR-----IKIKNLK--SALEKLDITDNIDIRIRQA 170
             |.:...|.|.| |.|||:| .:|....:.|.     :..|.::  .::::|....|......|.
  Fly   808 -RGSETLLPEYE-PDAEQELATKLSRSFDMKEEGGTLLGDKGVRRHQSMQRLSAEQNGGSTTEQT 870

  Fly   171 ELEYALGREELQMLSIVEEARA-LQARLEKSKPEAQTLYNIISSGVSLSLHA------VHATSGR 228
            .....         ::|.:.|. |...::|:||    :..|...|.:.:.|.      :|....
  Fly   871 HEHNP---------NVVPDHRGNLHITVKKTKP----ILGIAIEGGANTKHPLPRIINIHENGA- 921

  Fly   229 WAVQQRTDQPGFYVEWALEGDGLYKGDRILEINGRLVTGKSKEELQKQV----GNSGKCQ---MV 286
                            |.|..||..|..|||::|..|.|...:|:.:.:    .|..|.:   :|
  Fly   922 ----------------AFEAGGLEVGQLILEVDGTKVEGLHHQEVARLIAECFANREKAEITFLV 970

  Fly   287 VLRKKS-------------------------------------------------VPIPQKQ--- 299
            |..|||                                                 .|||..:
  Fly   971 VEAKKSNLEPKPTALIFLEAXHLLALPASDPLERQKLEFLYEWGIDLTETPKPMPTPIPLTKAKN 1035

  Fly   300 ---LDQEKENNMRLQHRISYLEEQVRELQTVKEHHPSQQQQQQQQQQQNPQQNPQQNPQQTSSNQ 361
               |..|..||:..|:..|   ..:...|..:..||..||||||||..|.:      ...|:||:
  Fly  1036 PPPLPHELHNNINSQYGSS---AALSNHQPHQHTHPHPQQQQQQQQHSNTK------TPNTNSNK 1091

  Fly   362 SQHVTSISISSPPSTPPEKPLIFQRGNYITTLVGGKPIELMGDDMAST----QTPPGHVTKTLIK 422
            :|           .||             ||          |...|:|    |..||:.|.|..|
  Fly  1092 TQ-----------GTP-------------TT----------GTGAATTGSKQQQQPGNTTNTPTK 1122

  Fly   423 ---------ENTHIDLRDRLSHMYSMPSKSLSASKISINS-DSAYMQHHRRDKERH--RDRQHRE 475
                     |..|........|....|::.....:..... .....|.|.||:::|  ..|:.||
  Fly  1123 ASREATPTREQHHQHATPTREHQQQTPTRQQQLQREQQQQLQREQQQQHHRDRQQHFREQREQRE 1187

  Fly   476 RPRDPLQQQQQLHREHLMSTHARSVEHLN---------HYNGLDRRRDTPRQSESNTLRA 526
            |......:.:|.|..|....|....:|.:         |::....::...|.|.||:.::
  Fly  1188 REYQHEHEHEQHHHHHHHREHHEQHQHQHGHQHHPQHQHHHQYSSQQQHQRYSSSNSYKS 1247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sprt	NP_610683.1	PDZ	<247..288	CDD:294084	14/47 (30%)
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492
		PDZ_signaling	466..543	CDD:238492
		HN_L-whirlin_R2_like	573..653	CDD:259823
		PDZ_signaling	886..971	CDD:238492	21/105 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900