Protein Alignment sprt and Cytip

DIOPT Version :9

• Sequence 1: NP_610683.1
• Gene: sprt / 246397
• FlyBaseID: FBgn0082585
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_631939.1
• Gene: Cytip / 227929
• MGIID: 2183535
• Length: 359
• Species: Mus musculus
• Alignment Length: 439
• Identity: 77/439 - (17%)
• Similarity: 135/439 - (30%)
• Gaps: 144/439 - (32%)

  Fly   138 TEAENKRIKIKNLKSALEKLDITDNIDIRIRQAELEYALGREELQM-----LSIVEEARALQARL 197
            |..:|:||::           :.|.:....|        ||::|.:     |.....::.....:
Mouse    35 TMEDNRRIQV-----------LADTVATLPR--------GRKQLALARSSSLGDFSWSQRKVVTV 80

  Fly   198 EKSKP-----EAQTL----YNIISSGVSLSLHAVHATSGRWAVQQRTDQPGFYVEWALEGDGLYK 253
            ||...     |.||.    .||.||.|...:..|           :.|.|....       ||..
Mouse    81 EKQDNGTFGFEIQTYRLQNQNICSSEVCTMICKV-----------QEDSPAHCA-------GLQV 127

  Fly   254 GDRILEINGRLVTGKSKEELQKQVGNSGKCQMVVLRKKSVPIPQKQLDQEKENNMRLQHRISYLE 318
            ||....:||....|.:.:::...:.:||....:                 :..|..:.||.:.||
Mouse   128 GDIFANVNGVSTEGFTHKQVVDLIRSSGNLLTI-----------------ETLNGTMIHRRAELE 175

  Fly   319 EQVREL-QTVKEHHPSQQQQQQQQQQQNPQQNPQQNPQQTSSNQSQHVTSISISSPPSTPPEKPL 382
            .:::.| ||:|:.....:....|:|:                        :......::|..:.:
Mouse   176 AKLQTLKQTLKKKWVELRSLHLQEQR------------------------LLHGDTANSPNLENM 216

  Fly   383 IFQRGNYITTLVGGKPIELMGDDMASTQTPPGHVTKTLIKENTHIDLRDRLSHMYSMPSKSLS-A 446
            .....:....|:|..|.                             |.||  |..|..|...| .
Mouse   217 DLDESSLFGNLLGPSPA-----------------------------LLDR--HRLSSESSCKSWL 250

  Fly   447 SKISINSDSAYMQHHRRDKERHR--------DRQHRERPRDPLQQQQQLHREHLMS-THARSVEH 502
            |.::::|:..|......|..|..        |.....:..|.:.:.....|...:| |.:.|...
Mouse   251 SSLTVDSEDGYRSSMSEDSIRGAFSRQTSTDDECFHSKDGDEILRNASSRRNRSISVTSSGSFSP 315

  Fly   503 LNHYNGLDRRRDTPRQSESNTLRAR----LPSDMRSVKSLDFDSENESK 547
            |...|........||:|...::|.:    :|...|:|:      |.||:
Mouse   316 LWESNYSSVFGTLPRKSRRGSVRKQILKFIPGLHRAVE------EEESR 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sprt	NP_610683.1	PDZ	<247..288	CDD:294084	9/40 (23%)
Cytip	NP_631939.1	PDZ_signaling	76..161	CDD:238492	22/119 (18%)
		Interaction with CYTH1. /evidence=ECO:0000250	166..188		8/21 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900