DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sprt and Pdzd3

DIOPT Version :9

Sequence 1:	NP_610683.1	Gene:	sprt / 246397	FlyBaseID:	FBgn0082585	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_573489.2	Gene:	Pdzd3 / 170761	MGIID:	2429554	Length:	498	Species:	Mus musculus

Alignment Length:	157	Identity:	34/157 - (21%)
Similarity:	58/157 - (36%)	Gaps:	40/157 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 SALEKLDIT----------DNIDIRIRQAELEYALGREELQMLSIVEEARALQAR-----LEKSK 201
            :::|||...          |.:.:.:...|:|....:..:.:.:.:.|..||.|:     :||.
Mouse   206 ASVEKLTYNQLNRKLWQSGDQVTLLVAGLEVEEQCHQLGMPLAAPLAEGWALPAKPRCLNIEKG- 269

  Fly   202 PEAQTLYNIISSGVSLSLHAVHATSGR-----WAVQQRTDQPGFYVEWALEGDGLYKGDRILEIN 261
            ||          |....|.......||     |.|     .||...:.|    |:..|||::.:.
Mouse   270 PE----------GFGFLLREEKGLDGRLGQFLWDV-----DPGLPADKA----GMKAGDRLVAVA 315

  Fly   262 GRLVTGKSKEELQKQVGNSGKCQMVVL 288
            |..|.|...||...::...|.|..:::
Mouse   316 GESVDGLGHEETVSRIRAQGSCVSLIV 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sprt	NP_610683.1	PDZ	<247..288	CDD:294084	11/40 (28%)
Pdzd3	NP_573489.2	PDZ_signaling	47..127	CDD:238492
		PDZ_signaling	155..232	CDD:238492	4/25 (16%)
		PDZ	260..345	CDD:214570	24/103 (23%)
		PDZ_signaling	407..471	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900