Protein Alignment sprt and USH1C

DIOPT Version :9

• Sequence 1: NP_610683.1
• Gene: sprt / 246397
• FlyBaseID: FBgn0082585
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: XP_016872564.1
• Gene: USH1C / 10083
• HGNCID: 12597
• Length: 956
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 78/420 - (18%)
• Similarity: 144/420 - (34%)
• Gaps: 126/420 - (30%)

  Fly   180 ELQMLSIVEEARALQARLEKSKPEAQTLYNIISSGVSLSLHAVHATSGRWAVQQRTDQPGFYVEW 244
            |...|:.....:..:.||::..||          |:.||:        |..::...   |.::..
Human    73 EYDQLTPRRSRKLKEVRLDRLHPE----------GLGLSV--------RGGLEFGC---GLFISH 116

  Fly   245 ALEGD-----GLYKGDRILEINGRLVTGKSKEELQKQVGNSGKCQMVVLRKKSVPIPQKQLDQEK 304
            .::|.     ||..||.|:.|||..::..:.||:..          ::..||:|.|
Human   117 LIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVIN----------LIRTKKTVSI--------- 162

  Fly   305 ENNMRLQHRISYLEEQVRELQTVK-EHHPSQQQQQQQQQQQNPQQNPQQNPQQTSSNQSQHVTSI 368
                           :||.:..:. :..|.:....|...|...:....:....:..|:......:
Human   163 ---------------KVRHIGLIPVKSSPDEPLTWQYVDQFVSESGGVRGSLGSPGNRENKEKKV 212

  Fly   369 SIS---------SPPSTPPEKPLIF----QRGNYITTL---VGGKPIELMGDDMASTQTPPGHVT 417
            .||         |..|.|.:||.||    :.|:....:   :|.:.:|:.|.|.
Human   213 FISLVGSRGLGCSISSGPIQKPGIFISHVKPGSLSAEVGLEIGDQIVEVNGVDF----------- 266

  Fly   418 KTLIKENTHIDLRDRLSHMYSMPSKSLSASKISINSDSAYMQHHRRDKERHRDRQHRERPRDP-- 480
                   :::|.::.::.:.|  |:||:.|.::......:|    .|:||..:.:.||..|..
Human   267 -------SNLDHKEAVNVLKS--SRSLTISIVAAAGRELFM----TDRERLAEARQRELQRQELL 318

  Fly   481 ------------LQQQQQLHREHLMSTHARSVEHLNHYNGLDRRRDTPRQSESNTLRARLPSDMR 533
                        ||:||::.|:.......::.|....|    |:.......|....:.:...|..
Human   319 MQKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERY----RKEMEQIVEEEEKFKKQWEEDWG 379

  Fly   534 SVKSLDFDSENESKPATETRTTRPTPPKKP 563
            |.:.|       ..|.|.|....|.|.:||
Human   380 SKEQL-------LLPKTITAEVHPVPLRKP 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sprt	NP_610683.1	PDZ	<247..288	CDD:294084	11/45 (24%)
USH1C	XP_016872564.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900