Protein Alignment mthl13 and Dh44-R1

DIOPT Version :10

• Sequence 1: NP_788325.2
• Gene: mthl13 / 246395
• FlyBaseID: FBgn0050018
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 416
• Identity: 84/416 - (20%)
• Similarity: 146/416 - (35%)
• Gaps: 130/416 - (31%)

  Fly    65 CSFKEHLFRTKLDLNIRLDDNSTEALYFNNQTLLITSF-----WD------------IDEMMGLR 112
            |..:||:            :.||   |.|:....:|.|     |.            :||:.|:
  Fly    35 CLVQEHI------------EAST---YGNDSGHCLTQFDSILCWPRTARGTLAVLQCMDELQGI- 83

  Fly   113 RDEYTLYKNGTIYIHSDQSIQTKEEYCFY-------------PHQIYSDFPETIWIISHKFSSIE 164
              .|...||.|.:.|::   .|.|:|..|             ..::..:.|..|:.|.:..|.:
  Fly    84 --HYDSSKNATRFCHAN---GTWEKYTNYDACAHLPAPESVPEFEVIVELPTIIYYIGYTLSLV- 142

  Fly   165 SPGAFELASGSIICYIIIFGIYLFVKELR--------NDFGKCVMSCVFCLFLDYLIWLMDELRL 221
                      |:...:|:|.   :.||||        |.|...:||.:|.:.   |:.:...:|.
  Fly   143 ----------SLSLALIVFA---YFKELRCLRNTIHANLFFTYIMSALFWIL---LLSVQISIRS 191

  Fly   222 LDDFCSLTGYIMFFFDFANSVWFSIISYCIWKKITSVVSQENRDQFVFYSTFAYGISAI------ 280
            ....|.....:..||...|..|..:....::..:....|.:|. :|..|::..:|..|:
  Fly   192 GVGSCIALITLFHFFTLTNFFWMLVEGLYLYMLVVKTFSGDNL-RFNIYASIGWGGPALFVVTWA 255

  Fly   281 ---PLGIIISINQFWEEDLRKWNWLPLVGFSRCSVDDCKRSSWVYYFVPYAIMCAINII--MFVL 340
               .|.:..|..:.:|.:.   .|:     ....||      |:|    ...:||:.||  .|:|
  Fly   256 VAKSLTVTYSTPEKYEINC---PWM-----QETHVD------WIY----QGPVCAVLIINLTFLL 302

  Fly   341 TIKHIMKTK-RNLHNLTKRPDRNET---CVTVNFLNFELYLLFL---RISGIMGVAWILIIFLLI 398
            .|..::.|| |:.:.:..|..|...   .|.:..... .||:.|   ..||:||..:.::..:|:
  Fly   303 RIMWVLITKLRSANTVETRQYRKAAKALLVLIPLFGI-TYLVVLAGPSESGLMGHMFAVLRAVLL 366

  Fly   399 EVNSTFWDIFGIIIQQIHYGFGIILF 424
            ...                ||.:.||
  Fly   367 STQ----------------GFSVSLF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl13	NP_788325.2	Mth_Ecto	<49..158	CDD:448329	25/122 (20%)
		7tm_GPCRs	186..440	CDD:475119	55/265 (21%)
		TM helix 2	197..218	CDD:410628	4/20 (20%)
		TM helix 3	227..249	CDD:410628	4/21 (19%)
		TM helix 4	269..285	CDD:410628	4/24 (17%)
		TM helix 5	316..339	CDD:410628	6/24 (25%)
		TM helix 6	376..397	CDD:410628	7/23 (30%)
		TM helix 7	402..431	CDD:410628	4/23 (17%)
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	15/65 (23%)
		7tmB1_DH_R	126..394	CDD:320391	62/304 (20%)
		TM helix 1	128..153	CDD:320391	7/38 (18%)
		TM helix 2	162..184	CDD:320391	6/24 (25%)
		TM helix 3	197..224	CDD:320391	4/26 (15%)
		TM helix 4	236..256	CDD:320391	4/19 (21%)
		TM helix 5	279..308	CDD:320391	11/38 (29%)
		TM helix 6	322..349	CDD:320391	5/27 (19%)
		TM helix 7	356..381	CDD:320391	5/37 (14%)