DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT2 and GSTO1

DIOPT Version :9

Sequence 1:	NP_724816.3	Gene:	GstT2 / 246386	FlyBaseID:	FBgn0050005	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_004823.1	Gene:	GSTO1 / 9446	HGNCID:	13312	Length:	241	Species:	Homo sapiens

Alignment Length:	146	Identity:	35/146 - (23%)
Similarity:	54/146 - (36%)	Gaps:	52/146 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 DEYKK------INRFQKVPAIVGGDFHLSETIAIIR------YLADKGQFDEKLYPKTLE----- 92
            |.|:|      :..|.|||::||         :.||      |...|.:| .|.:.|..|
Human   106 DPYEKACQKMILELFSKVPSLVG---------SFIRSQNKEDYAGLKEEF-RKEFTKLEEVLTNK 160

  Fly    93 -------NRARVDEFLEWQHLNIRLACSMYFRDA---------WLFPMNGIAPKPKPEQIQALIE 141
                   |...:.::|.|.... ||. :|...:.         |:..|     |..| .:.||:.
Human   161 KTTFFGGNSISMIDYLIWPWFE-RLE-AMKLNECVDHTPKLKLWMAAM-----KEDP-TVSALLT 217

  Fly   142 GVENNLGLLERLWLEN 157
            ..::..|.|| |:|:|
Human   218 SEKDWQGFLE-LYLQN 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT2	NP_724816.3	GST_N_Theta	5..80	CDD:239348	12/46 (26%)
		GstA	7..202	CDD:223698	35/146 (24%)
		GST_C_family	93..218	CDD:295467	18/74 (24%)
GSTO1	NP_004823.1	GST_N_Omega	5..94	CDD:239353
		Glutathione binding. /evidence=ECO:0000269\|PubMed:10783391, ECO:0000269\|PubMed:21106529	85..86
		GST_C_Omega	108..229	CDD:198293	31/139 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154248
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840