DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT2 and clic3

DIOPT Version :9

Sequence 1:	NP_724816.3	Gene:	GstT2 / 246386	FlyBaseID:	FBgn0050005	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_955818.1	Gene:	clic3 / 84040	ZFINID:	ZDB-GENE-010507-2	Length:	239	Species:	Danio rerio

Alignment Length:	157	Identity:	29/157 - (18%)
Similarity:	51/157 - (32%)	Gaps:	61/157 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 CSMYFRDAWL----FPMNGIAPKPKPEQIQALIEG-----------VENNLGLLERLWLENDFLV 161
            |...|...||    |.:..:..|..||.::.|..|           |..:...:|      :||
Zfish    26 CQRLFMILWLKGVNFTLTTVDMKRAPEVLKDLAPGSQPPFLIYNGEVRTDTNKIE------EFL- 83

  Fly   162 GKNLTMADILGSSEINQLRLCQYRVD--------------------------EKKFPKVVKWLER 200
                  .|.|...:..:| .|:|:..                          ||||.|.:..|::
Zfish    84 ------EDTLAPPQYPKL-CCRYKESNTAGDDIFHKFSAYIKNPNPGLNDMLEKKFLKSLMKLDQ 141

  Fly   201 VRVSANPYHDEGLTFIDRKSKQSTAAK 227
            ..::..|:.      :|:..:.||:.:
Zfish   142 YLLTPLPHE------LDQNPELSTSTR 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT2	NP_724816.3	GST_N_Theta	5..80	CDD:239348
		GstA	7..202	CDD:223698	25/130 (19%)
		GST_C_family	93..218	CDD:295467	26/146 (18%)
clic3	NP_955818.1	GST_N_CLIC	3..92	CDD:239359	16/78 (21%)
		O-ClC	6..237	CDD:129941	29/157 (18%)
		GST_C_CLIC3	99..231	CDD:198332	11/70 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589578
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930