DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstT2 and GDAP1

DIOPT Version :10

Sequence 1:NP_724816.3 Gene:GstT2 / 246386 FlyBaseID:FBgn0050005 Length:228 Species:Drosophila melanogaster
Sequence 2:NP_061845.2 Gene:GDAP1 / 54332 HGNCID:15968 Length:358 Species:Homo sapiens


Alignment Length:191 Identity:38/191 - (19%)
Similarity:74/191 - (38%) Gaps:42/191 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    47 YKKINRFQKVPAIVGGDFHLSETIAIIRYLADKGQFDEK-----------LYPKTLENRARVDEF 100
            :.::|...:||.::.|:..:.|...||.|| ::...||:           .||:....|..:|. 
Human    68 FMRLNSTGEVPVLIHGENIICEATQIIDYL-EQTFLDERTPRLMPDKESMYYPRVQHYRELLDS- 130

  Fly   101 LEWQHLNIRLACSMYFRDAWLFP---MNGIAPKPKPEQIQALIEGVENNLGLLERLWLENDFLVG 162
                     |....|.....|.|   ::.:.|.....:|::.|...|:.   |::|..||     
Human   131 ---------LPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESE---LKKLAEEN----- 178

  Fly   163 KNLTMADILGSSEINQLRLCQYRVDEKKFPKVVKWLERVRVSANPYHDEGLTFIDRKSKQS 223
                 .|:..:....|.||....:|...    ||:|:::........|:..|.:.|:::::
Human   179 -----PDLQEAYIAKQKRLKSKLLDHDN----VKYLKKILDELEKVLDQVETELQRRNEET 230

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstT2NP_724816.3 GST_N_Theta 5..80 CDD:239348 9/32 (28%)
GST_C_family 93..218 CDD:470672 24/127 (19%)
GDAP1NP_061845.2 GST_N_GDAP1 26..98 CDD:239350 9/30 (30%)
GST_C_GDAP1 179..289 CDD:198336 11/56 (20%)
Required for mitochondrial localization 320..358
Blue background indicates that the domain is not in the aligned region.

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