DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstT2 and Clic6

DIOPT Version :9

Sequence 1:	NP_724816.3	Gene:	GstT2 / 246386	FlyBaseID:	FBgn0050005	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_788267.2	Gene:	Clic6 / 304081	RGDID:	727938	Length:	613	Species:	Rattus norvegicus

Alignment Length:	235	Identity:	48/235 - (20%)
Similarity:	72/235 - (30%)	Gaps:	103/235 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 DEYKKIN-RFQKVPAIVGGDFHLSETIAIIRYLADKGQ------FDEKLY--------------- 87
            :|..::| |.:..||...||......|.:.......|:      |.::|:
  Rat   354 EELGRVNGRRENGPASEEGDLGQEHDITLFVKAGSDGESIGNCPFSQRLFMILWLKGVIFNVTTV 418

  Fly    88 -----PKTLENRA-------------------RVDEFLE------------WQHLNIRLACSMYF 116
                 |..|:|.|                   :::||||            .||.....|.:..|
  Rat   419 DLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLVPPRYPKLGTQHPESNSAGNDVF 483

  Fly   117 -----------RDAWLFPMNGIAPK---------------PKPEQIQAL-IEGVENNLGLLERLW 154
                       :||     |.|..|               |.|::|.|. .|.|..:
  Rat   484 AKFSAFIKNTKKDA-----NDIYEKNLLRALKKLDSYLNSPLPDEIDAYSTEDVTVS-------- 535

  Fly   155 LENDFLVGKNLTMAD--ILGSSEINQLRLCQYRVDEKKFP 192
             :..||.|..||:||  :|....|.::...:||..|  ||
  Rat   536 -QRKFLDGDELTLADCNLLPKLHIIKIVAKKYRGFE--FP 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT2	NP_724816.3	GST_N_Theta	5..80	CDD:239348	8/35 (23%)
		GstA	7..202	CDD:223698	48/235 (20%)
		GST_C_family	93..218	CDD:295467	35/160 (22%)
Clic6	NP_788267.2	2A1904	<51..318	CDD:273344
Clic6	NP_788267.2	O-ClC	380..613	CDD:129941	41/209 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348019
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930