Protein Alignment GstT2 and GSTT1

DIOPT Version :10

• Sequence 1: NP_724816.3
• Gene: GstT2 / 246386
• FlyBaseID: FBgn0050005
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: XP_054181554.1
• Gene: GSTT1 / 2952
• HGNCID: 4641
• Length: 289
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 69/253 - (27%)
• Similarity: 117/253 - (46%)
• Gaps: 58/253 - (22%)

  Fly     5 IRFYYDLLSPIARGLWIGLKFSNSPVEY-----------------CPIALRKF------------ 40
            :..|.||||...|.::|..|.::.|.|.                 |.:..|:.
Human     3 LELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGALPVFANQECRLVGRRTVKLGPEHCREGH 67

  Fly    41 --------------------EQLTDEYKKINRFQKVPAIVGGDFHLSETIAIIRYLADKGQFDEK 85
                                :.|:|.:.::|..:||||:..|||.|:|::||:.||..|.:..:.
Human    68 RPWRAQRSPPTTHHAGLFPGQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLYLTRKYKVPDY 132

  Fly    86 LYPKTLENRARVDEFLEWQHLNIRLACSMYFRDAW---LFPMNGIAPKPKPEQIQALIEGVENNL 147
            .||:.|:.||||||:|.|||..:|.:|   .|..|   :||: .:.....|:.:.|.:..::..|
Human   133 WYPQDLQARARVDEYLAWQHTTLRRSC---LRALWHKVMFPV-FLGEPVSPQTLAATLAELDVTL 193

  Fly   148 GLLERLWLEND-FLVGKNLTMADILGSSEINQLRLCQYRVDEKKFPKVVKWLERVRVS 204
            .|||..:|:|. ||.|.::::||::..:|:........:|.|.: ||:..|.:||..:
Human   194 QLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGR-PKLATWRQRVEAA 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstT2	NP_724816.3	GST_N_Theta	5..80	CDD:239348	28/123 (23%)
		GST_C_family	93..218	CDD:470672	37/116 (32%)
GSTT1	XP_054181554.1	GST_N_Theta	3..127	CDD:239348	28/123 (23%)
		GST_C_Theta	140..265	CDD:198292	37/116 (32%)