DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT2 and Clic6

DIOPT Version :9

Sequence 1:	NP_724816.3	Gene:	GstT2 / 246386	FlyBaseID:	FBgn0050005	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_766057.1	Gene:	Clic6 / 209195	MGIID:	2146607	Length:	596	Species:	Mus musculus

Alignment Length:	231	Identity:	48/231 - (20%)
Similarity:	81/231 - (35%)	Gaps:	79/231 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 GDFHLSETIAIIRYLADKG------QFDEKLYPKTLENRA-------------------RVDEFL 101
            |:...|:.:.:|.:|  ||      ..|.|..|..|:|.|                   :::|||
Mouse   377 GNCPFSQRLFMILWL--KGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFL 439

  Fly   102 E------------WQHLNIRLACSMYF-----------RDA----------WLFPMNGIAPKPKP 133
            |            .||.....|.:..|           :||          .|..::.....|.|
Mouse   440 EEKLVPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIYEKNLLRALKKLDSYLNSPLP 504

  Fly   134 EQIQALIEGVENNLGLLERLWLENDFLVGKNLTMADILGSSEINQLRLCQYRVDEKKFPKVVK-- 196
            ::|.|   ....::.:.:|     .||.|..||:||.....:::.:::...:..:.:||..:.
Mouse   505 DEIDA---DSSEDVTVSQR-----KFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFPSEMTGI 561

  Fly   197 WLERVRVSANPYHDEGLTF---IDRKSKQ--STAAK 227
            |    |...|.|..:..|.   .||:.:.  |.|||
Mouse   562 W----RYLNNAYARDEFTNTCPADREIEHAYSDAAK 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT2	NP_724816.3	GST_N_Theta	5..80	CDD:239348	4/17 (24%)
		GstA	7..202	CDD:223698	38/199 (19%)
		GST_C_family	93..218	CDD:295467	32/181 (18%)
Clic6	NP_766057.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..360
		PHA02664	<69..167	CDD:177447
		GST_N_CLIC	360..448	CDD:239359	16/72 (22%)
		O-ClC	363..596	CDD:129941	48/231 (21%)
		GST_C_CLIC6	455..594	CDD:198334	31/151 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844580
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930