DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT2 and Gstt2

DIOPT Version :9

Sequence 1:	NP_724816.3	Gene:	GstT2 / 246386	FlyBaseID:	FBgn0050005	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	XP_011241675.1	Gene:	Gstt2 / 14872	MGIID:	106188	Length:	251	Species:	Mus musculus

Alignment Length:	212	Identity:	64/212 - (30%)
Similarity:	104/212 - (49%)	Gaps:	25/212 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IRFYYDLLSPIARGLWIGLKFSNSPVEYCPIALRKFEQLTDEYKKINRFQKVPAIVGGDFHLSE- 68
            :..|.||||..:|.::|..|.:..|.:...:.:.|.:.:::::.::|...|||.:..|.|.|:|
Mouse     3 LELYLDLLSQPSRAVYIFAKKNGIPFQTRTVDILKGQHMSEQFSQVNCLNKVPVLKDGSFVLTES 67

  Fly    69 ------TIAIIRYLADKGQFDEKLYPKTLENRARVDEFLEWQHLNIRLACSMYFRDAWLFPMNGI 127
                  :.||:.||:.|.|..:..||..|:.||:|.|:|.|...|||....:......|.|:.|
Mouse    68 PSSMIPSTAILIYLSSKYQVADHWYPADLQARAQVHEYLGWHADNIRGTFGVLLWTKVLGPLIG- 131

  Fly   128 APKPKPEQIQALIEGVENN-------LGLLERLWL-ENDFLVGKNLTMADILGSSEINQLRLCQY 184
                    :|...|.||.|       |..||..:| :..||||:.:|:||::...|:.|.....|
Mouse   132 --------VQVPQEKVERNRDRMVLVLQQLEDKFLRDRAFLVGQQVTLADLMSLEELMQPVALGY 188

  Fly   185 RVDEKKFPKVVKWLERV 201
            .:.|.: |::..|.|||
Mouse   189 NLFEGR-PQLTAWRERV 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT2	NP_724816.3	GST_N_Theta	5..80	CDD:239348	22/81 (27%)
		GstA	7..202	CDD:223698	64/210 (30%)
		GST_C_family	93..218	CDD:295467	37/117 (32%)
Gstt2	XP_011241675.1	GST_N_Theta	3..85	CDD:239348	22/81 (27%)
Gstt2	XP_011241675.1	GST_C_Theta	98..223	CDD:198292	37/117 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844517
Domainoid	1	1.000	61	1.000	Domainoid score	I10389
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4379
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54888
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	O	PTHR43917
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.770