Protein Alignment GstT2 and CLIC2

DIOPT Version :9

• Sequence 1: NP_724816.3
• Gene: GstT2 / 246386
• FlyBaseID: FBgn0050005
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_001280.3
• Gene: CLIC2 / 1193
• HGNCID: 2063
• Length: 247
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 47/214 - (21%)
• Similarity: 79/214 - (36%)
• Gaps: 73/214 - (34%)

  Fly    19 LWI-GLKFSNSPVEYCPIALRKFEQLTD-------EYKKINRFQKVPAIVGGDFHLSETIAIIRY 75
            ||: |:||:.:.|:    ..||.|:|.|       .:...|:..|...|...:| |.:|:|..||
Human    40 LWLKGVKFNVTTVD----MTRKPEELKDLAPGTNPPFLVYNKELKTDFIKIEEF-LEQTLAPPRY 99

  Fly    76 LADKGQFDEKLYPKTLENRARVDEFLEWQHLNIRLACSMYFR-DAWLFPMNGIAPKPKPEQIQAL 139
                    ..|.||..|              :..:.|:::.: .|::......|.|...:.:...
Human   100 --------PHLSPKYKE--------------SFDVGCNLFAKFSAYIKNTQKEANKNFEKSLLKE 142

  Fly   140 IEGVEN--NLGLLERLWLEND-----------FLVGKNLTMADILGSSEINQLRLCQYRVDEKKF 191
            .:.:::  |..||:.  ::.|           ||.|..||:||            |..      .
Human   143 FKRLDDYLNTPLLDE--IDPDSAEEPPVSRRLFLDGDQLTLAD------------CSL------L 187

  Fly   192 PKVVKWLERVRVSANPYHD 210
            ||    |..::|:|..|.|
Human   188 PK----LNIIKVAAKKYRD 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstT2	NP_724816.3	GST_N_Theta	5..80	CDD:239348	20/68 (29%)
		GstA	7..202	CDD:223698	43/204 (21%)
		GST_C_family	93..218	CDD:295467	23/132 (17%)
CLIC2	NP_001280.3	Required for insertion into the membrane. /evidence=ECO:0000250	1..96		17/60 (28%)
		N-terminal	1..94		16/58 (28%)
		O-ClC	12..245	CDD:129941	47/214 (22%)
		Joint loop	95..106		5/18 (28%)
		C-terminal	107..247		24/134 (18%)
		Foot loop	151..171		4/21 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154389
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930