| Sequence 1: | NP_062094.1 | Gene: | Tp63 / 246334 | RGDID: | 620863 | Length: | 680 | Species: | Rattus norvegicus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_996267.1 | Gene: | p53 / 2768677 | FlyBaseID: | FBgn0039044 | Length: | 495 | Species: | Drosophila melanogaster |
| Alignment Length: | 512 | Identity: | 105/512 - (20%) |
|---|---|---|---|
| Similarity: | 184/512 - (35%) | Gaps: | 112/512 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Rat 29 FSWKESYYRSAMSQSTQTSEFLSPEVFQHIWDFLEQPICSVQPIDLNFVDEPSENGATNKIEISM 93
Rat 94 DCIRMQDSDLSDPMWPQYTNLGLLNGMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDA 158
Rat 159 LSPSPAIPSNTDYP------------GPHSF------------------------DVSFQQSSTA 187
Rat 188 K-------------------SATWTYSTELKKLYCQIAKTCPIQIKVMTPPP-QGAVIRAMPVYK 232
Rat 233 KAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVE-------GNSHAQYVEDPITGRQSVLVPY 290
Rat 291 ----EPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRD 351
Rat 352 RKADE---DSIRKQQVSDSAKNGDGTK--RPFRQNTHGIQMTSIKK----------RRSPD-DEL 400
Rat 401 LYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSMQSQS 457 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Tp63 | NP_062094.1 | Transcription activation. /evidence=ECO:0000250 | 1..107 | 16/77 (21%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 122..171 | 9/48 (19%) | |||
| P53 | 163..358 | CDD:279242 | 55/264 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 351..393 | 10/56 (18%) | |||
| Interaction with HIPK2. /evidence=ECO:0000250 | 352..388 | 9/40 (23%) | |||
| P53_tetramer | 391..431 | CDD:285011 | 9/50 (18%) | ||
| Oligomerization. /evidence=ECO:0000250 | 394..443 | 12/49 (24%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 436..472 | 4/22 (18%) | |||
| Forkhead_N | 452..>534 | CDD:254796 | 1/6 (17%) | ||
| SAM | 541..606 | CDD:197735 | |||
| SAM_tumor-p63 | 543..607 | CDD:188971 | |||
| Transactivation inhibition. /evidence=ECO:0000250 | 610..680 | ||||
| p53 | NP_996267.1 | P53 | 203..383 | CDD:176262 | 47/188 (25%) |
| P53_C | 429..495 | CDD:288471 | 14/71 (20%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C166340689 | |
| Domainoid | 1 | 1.000 | 65 | 1.000 | Domainoid score | I9777 |
| eggNOG | 1 | 0.900 | - | - | E1_2C1DX | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0002925 | |
| OrthoInspector | 1 | 1.000 | - | - | otm45413 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR11447 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 9 | 8.800 | |||||