DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Slc36a2 and CG32081

DIOPT Version :9

Sequence 1:	NP_647555.2	Gene:	Slc36a2 / 246235	RGDID:	620492	Length:	481	Species:	Rattus norvegicus
Sequence 2:	NP_729646.1	Gene:	CG32081 / 326194	FlyBaseID:	FBgn0052081	Length:	471	Species:	Drosophila melanogaster

Alignment Length:	426	Identity:	122/426 - (28%)
Similarity:	201/426 - (47%)	Gaps:	48/426 - (11%)

- Green bases have known domain annotations that are detailed below.

  Rat    61 LVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRLNKPFMDYGDTV 125
            |:|..:|||::.:||:...|||:.|.:.|:.:..:..|.|.:|:.|......|:...:..|...:
  Fly    28 LLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIICMIECSRRMQIGYATYPVAM 92

  Rat   126 MHGLASSPNTWLQSHAHWGRHVVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNET 190
            ::.....|. :.:..:..||::|...|..:|.|.|.||.||:|..|||:|:
  Fly    93 VYSFDQGPR-FFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAATLKQLVD-------------- 142

  Rat   191 VVLTPTIDSRLYMLAFLPVLGLLVF----IRNLRVLTIFSLLANVSMLVSLVIIAQYIIQGIPDP 251
             ......|.|:|    :.|:.|.:.    ||.|:.|..|::||::.:.....::..|:...:|..
  Fly   143 -FYWVVADLRIY----IAVIALCLIPPFQIRKLKYLVPFNILASILIYTGFSLMMYYLFVDLPPI 202

  Rat   252 SQLP-LVASWKTYPLFFGTAIFSFESIGVVLPLENKMKDARRFP---TILSLGMSIITTLYIAIG 312
            ::.. |.......|||||.|:||..|:||:|.:|..|...|.:.   .||...:.::...|:..|
  Fly   203 TERNILFGRIDKIPLFFGIALFSITSVGVMLAVEATMAKPRHYLGWFGILDRAILLVIISYVTFG 267

  Rat   313 ALGYLRFGDDIKASITLNLP-NCWLYQSVKLLYVVGILCTYALQFYVPAEIIIPLAVSQVSKRWA 376
            .:||.|:||:...||:||:| :..|.|..|......|..||.|..:|..:||       ::..|.
  Fly   268 LMGYWRYGDETAGSISLNIPTDEVLSQVAKGFIAAAIFLTYPLAGFVIIDII-------MNHFWN 325

  Rat   377 LPVDLS--------IRLALVCLTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVTTY---- 429
            ...||.        :|...|.|.|:.||:.|.|..:|||||:::.|.|.|:.|.|:|:..|
  Fly   326 KNGDLPNAALKESILRACTVVLICITAIIAPNLGPLLSLVGALTISLLNLVFPALIEICLYYPPE 390

  Rat   430 YGEGMSPLTITKDALISILGFMGFVVGTYQALDELI 465
            |..|.....:.||....|:|.:..|.||..::.::|
  Fly   391 YNYGKLKWVLVKDIFYVIVGILILVQGTVFSIKDMI 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slc36a2	NP_647555.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..49
Slc36a2	NP_647555.2	SLC5-6-like_sbd	50..461	CDD:382020	121/420 (29%)
CG32081	NP_729646.1	SLC5-6-like_sbd	17..422	CDD:294310	121/420 (29%)
CG32081	NP_729646.1	SdaC	20..415	CDD:223884	118/413 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352614
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940