DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Serpine1 and Spn42Dd

DIOPT Version :9

Sequence 1:	NP_036752.2	Gene:	Serpine1 / 24617	RGDID:	3249	Length:	402	Species:	Rattus norvegicus
Sequence 2:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	110/366 - (30%)
Similarity:	183/366 - (50%)	Gaps:	17/366 - (4%)

- Green bases have known domain annotations that are detailed below.

  Rat    41 KVFQHVVQASKDRNVVFSPYGVSSVLAMLQLTTAGKTRQQIQDAMGFNISERGTAPALR--KLSK 103
            :::|.:.::..::|:|.||..:.::|:|:.:...|.|.:::|.|:|.. ||...|.|.|  .|..
  Fly    20 EIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLP-SEDKEAVAARYGALLN 83

  Rat   104 ELMGSWNKNEISTADAIFVQRDLELVQGFMPHFFKLFRTTVKQVDFSEMERARFIINDWVERHTK 168
            :|.|......:..|:.|:|.....|.|.:.....:.|::..:.:..:....|...||.||...|.
  Fly    84 DLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQTS 148

  Rat   169 GMISDLLAKGAVNELTRLVLVNALYFNGQWKTPFLEASTHQRLFHKSDGSTISVPMMAQNNKFNY 233
            |.|..::..|::....:.:||||:||.|||::.|..|.|....|..:...::.|.||||...|..
  Fly   149 GKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRA 213

  Rat   234 TEFTTPDGHEYDILELPYHGETLSMFIAAPFEKDVPLSAITNILDAELIRQWKSNMTRLPRLLIL 298
            ..|...|.   .::||||....|||.|..|.|.: .|||:     .|.|..:...:......|.|
  Fly   214 NYFRDLDA---QVIELPYLNSNLSMTIFLPREVE-GLSAL-----EEKIVGFARPLVAKEVYLKL 269

  Rat   299 PKFSLETEVDLRGPLEKLGMTDIFSSTQADFTSL-SDQEQLSVAQALQKVKIEVNESGTVASSST 362
            |||.:|...:|:..|||||:.::|:. ::|.:.| :|:....|:|...|..:||||.|..|:.:|
  Fly   270 PKFKIEFRDELKETLEKLGIRELFTD-KSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGAT 333

  Rat   363 AILVSARMA-PTEMVLDRSFLFVVRHNPTETILFMGQLMEP 402
            ::.|:.|.. .|.::.|..|.||:|  ...||.|.|:::.|
  Fly   334 SVAVTNRAGFSTFLMADHPFAFVIR--DANTIYFQGRVVSP 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Serpine1	NP_036752.2	serpin	29..402	CDD:422956	109/364 (30%)
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	109/361 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020