Protein Alignment Npr1 and Gyc88E

DIOPT Version :10

• Sequence 1: NP_036745.1
• Gene: Npr1 / 24603
• RGDID: 3195
• Length: 1057
• Species: Rattus norvegicus
• Sequence 2: NP_001036711.1
• Gene: Gyc88E / 41825
• FlyBaseID: FBgn0038295
• Length: 1097
• Species: Drosophila melanogaster
• Alignment Length: 721
• Identity: 207/721 - (28%)
• Similarity: 309/721 - (42%)
• Gaps: 182/721 - (25%)

  Rat   374 ENITQRMWNRSFQGVTGYLKIDRNGDRDT-DFSLWDMDPETGAFRVVLNYNGTSQELMAVSEHKL 437
            ||:::  :.:|..|...:..|.|....|: .||:..:.||    .::......:|:::.|||...
  Fly     7 ENLSE--YIKSVYGEEKWEDIRRQAGIDSPSFSVHQVYPE----NLLQKLAKKAQQVLGVSERDF 65

  Rat   438 YWPLG-YPPPDVPKCGFDNEDPACNQDHFSTLEVLA------LVGSLSLISFLIVSFFIYRKMQL 495
            ...:| |....|.:.|:|.           .|.||.      |.|..:|..:|   .|.|.:|:
  Fly    66 MDQMGVYFVGFVGQYGYDR-----------VLSVLGRHMRDFLNGLDNLHEYL---KFSYPRMR- 115

  Rat   496 EKELVSELWRVRWEDLQPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKGNLV 560
                            .||.:..:....|  |||..|....|.:..|.||.:..|:..|:|
  Fly   116 ----------------APSFICENETKQG--LTLHYRSKRRGFVYYTMGQIREVARYFYHK---- 158

  Rat   561 AVKRVNRKRIELTR-KVLFELKHMR---DVQNEHLTRFVGACTD-----PPNICILTEYCP---- 612
                  ...|||.| ::||:..|:.   ...|...|....|.|.     |.:..:|.|..|
  Fly   159 ------EMHIELVREEILFDTVHVTFQLTFDNRAFTLASLAMTREEKHLPISAHVLFEIFPFCMV 217

  Rat   613 ----------RGSLQDILE---NESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVV 664
                      ..||..||.   .:.||. |.       |:|:.::......|.:..|
  Fly   218 FGADMVVRSIGNSLMVILPELLGKKITA-WF-------DLVRPLIAFKFQTILNRTN-------- 266

  Rat   665 DGRFVLKITDYGLESFRDPEPEQGHTLFAKKLWTAPELLRMASPPARGSQAGDVYSFGIILQEIA 729
             ..|.|...|...|.|    ..|...|...:..:.||                        :.:.
  Fly   267 -NIFELVTVDPVTERF----DVQNEDLLQHEDGSEPE------------------------KSLR 302

  Rat   730 LRSGVFYVE--------GLDLSPKEIIERVTRGEQPPFRPSMDLQSHLEELGQLMQRCWAEDPQE 786
            |:..:.|:|        |..:.| ::...:|.|..               :..|....::.|...
  Fly   303 LKGQMVYMENWRMIMFLGTPVMP-DLTSLITTGLY---------------INDLSMHDFSRDLML 351

  Rat   787 RPPFQQIRLALRKFNKENSSNILDNLLSRMEQYANNLEE---LVEERTQAYLEEKRKAEALLYQI 848
            ....|.:.|.|              .|.:.:|.:..|||   |::       ||.|:.:.||||:
  Fly   352 AGTQQSVELKL--------------ALDQEQQKSKKLEESMRLLD-------EEMRRTDELLYQM 395

  Rat   849 LPHSVAEQLKRGETV--QAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNF 911
            :|..||::|:|||..  ..|.||||:|.|||||.||.:.:..|||:||::||.:|:.||.:.:..
  Fly   396 IPKQVADRLRRGENPIDTCEMFDSVSILFSDIVTFTEICSRITPMEVVSMLNAMYSIFDKLTERN 460

  Rat   912 DVYKVETIGDAYMVVSGLPVRNGQLHAREVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPV 976
            .||||||||||||||:|.|.::.. ||..|..|||.::||:...:.....| .||:|:|:|:|.|
  Fly   461 SVYKVETIGDAYMVVAGAPDKDAN-HAERVCDMALDMVDAITDLKDPSTGQ-HLRIRVGVHSGAV 523

  Rat   977 CAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFDGFELELRGDVEMKGKGK 1041
            .||:|||||||||||||||||||||||...|:|:|:|..||.::.  ..:::..||::::||||.
  Fly   524 VAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISESTKVLIG--PNYKIIERGEIDVKGKGT 586

  Rat  1042 VRTYWL 1047
            :.||||
  Fly   587 MGTYWL 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Npr1	NP_036745.1	PBP1_NPR_A	32..439	CDD:380608	15/65 (23%)
		PK_GC-A_B	530..803	CDD:270944	55/306 (18%)
		HNOBA	<809..857	CDD:462234	16/50 (32%)
		CYCc	836..1025	CDD:214485	100/190 (53%)
Gyc88E	NP_001036711.1	HNOB	2..163	CDD:462233	44/204 (22%)
		HNOBA	201..404	CDD:462234	52/284 (18%)
		CYCc	383..571	CDD:214485	100/191 (52%)
		PHA03307	794..>955	CDD:223039