DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Npr1 and CG32301

DIOPT Version :9

Sequence 1:	NP_036745.1	Gene:	Npr1 / 24603	RGDID:	3195	Length:	1057	Species:	Rattus norvegicus
Sequence 2:	NP_728724.2	Gene:	CG32301 / 38285	FlyBaseID:	FBgn0052301	Length:	1111	Species:	Drosophila melanogaster

Alignment Length:	249	Identity:	66/249 - (26%)
Similarity:	120/249 - (48%)	Gaps:	37/249 - (14%)

- Green bases have known domain annotations that are detailed below.

  Rat   807 NILDNLLSRMEQYANNLEELVEERTQ----------AYLEEKRKAEALLYQILPHSVAEQLK--- 858
            |:|...|||.::|  |:...:..|.|          |..|||    |||..|:|.::|..|:
  Fly   205 NMLCMFLSRFQEY--NMRSGILSRYQVVYQNLVFQMAMKEEK----ALLDSIIPVTLARSLQDAI 263

  Rat   859 ---------------RGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVI 908
                           :...:..|....|:|..:|:|.||.|:.......:|.:|::|:..||...
  Fly   264 ASHIEEDPSNLMPFTKTRHLFMEPHPEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAA 328

  Rat   909 DNFDVYKVETIGDAYMVVSGLPVRNGQLHAREVARMALALLDAVRSFRIRHRPQEQLRLRIGIHT 973
            ::....:::.:||:|..|:|:| .....||......||.:::..|  .:..|..:::.||||:|:
  Fly   329 NHNRATRIKFLGDSYTCVTGIP-SYFPTHANACVNQALDMIEISR--EVSKRRNKKIDLRIGVHS 390

  Rat   974 GPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFDGFE 1027
            |.:.||::||...::.::...|:..:|:||:|....:|:||.|..:|:....:|
  Fly   391 GEILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGMVHISSRTLGLLDNHYVYE 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Npr1	NP_036745.1	PBP1_NPR_A	32..439	CDD:107380
		ANF_receptor	50..410	CDD:279440
		PK_GC-A_B	530..803	CDD:270944
		TyrKc	543..797	CDD:197581
		HNOBA	<812..857	CDD:285003	17/54 (31%)
		CYCc	836..1025	CDD:214485	55/206 (27%)
		Guanylate_cyc	863..1049	CDD:278633	46/165 (28%)
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	45/158 (28%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900