Protein Alignment ATP6V0D2 and VhaAC39-2

DIOPT Version :10

• Sequence 1: NP_689778.1
• Gene: ATP6V0D2 / 245972
• HGNCID: 18266
• Length: 350
• Species: Homo sapiens
• Sequence 2: NP_651128.1
• Gene: VhaAC39-2 / 42739
• FlyBaseID: FBgn0039058
• Length: 350
• Species: Drosophila melanogaster
• Alignment Length: 345
• Identity: 142/345 - (41%)
• Similarity: 221/345 - (64%)
• Gaps: 2/345 - (0%)

Human     7 LYFNVDHGYLEGLVRGCKASLLTQQDYINLVQCETLEDLKIHLQTTDYGNFLANHTNPLTVSKID 71
            :.||.::||||.|.||.|..:|...||:||.|||:|||:.|.:|.||||.......:..:|..|:
  Fly     3 MIFNTEYGYLEALTRGFKNGMLKHSDYLNLTQCESLEDVMISIQGTDYGLIFGGEQSAPSVEVIE 67

Human    72 TEMRKRLCGEFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQKKSVKEILGKCHPLGRFT 136
            ..:|.||..::.|.|:||.|||:||:.::...:|||||.||:.|....:|:|.:|..|||||.|.
  Fly    68 RCLRDRLLQQYYYIRSHSTEPLTTFMEFIRYPFMIDNVALLVAGLNNHRSMKRLLRMCHPLGEFD 132

Human   137 EMEAVNIAETPSDLFNAILIETPLAPFFQDCMSENALDELNIELLRNKLYKSYLEAFYKFCKNHG 201
            ::.|:.:|...::||:|:||:||:|.|....:...:|..|::|::|..||::|||.||.:|...|
  Fly   133 QLGAIEVASNSAELFDAVLIDTPIARFVPRDLPMESLRYLDVEIVRAHLYRAYLEKFYAYCSQLG 197

Human   202 DVTAEVMCPILEFEADRRAFIITLNSFGTELSKEDRETLYPTFGKLYPEGLRLLAQAEDFDQMKN 266
            ..||.||..:|.||||||...|.:|:.|:::..::|..::||.|.|....|..::...|.|::::
  Fly   198 GNTANVMTNLLSFEADRRTITIAVNAIGSDIIPKERLKMFPTCGYLPKIALASMSTLNDTDKIRD 262

Human   267 VADHYGVYKPLFEAV--GGSGGKTLEDVFYEREVQMNVLAFNRQFHYGVFYAYVKLKEQEIRNIV 329
            |.:.:..|..:|:.:  ...|..||||.|...|.:.||..|.:|:|:|:||:::|||:.|:||||
  Fly   263 VCNVFDGYGKMFDNLERDSDGMITLEDRFLMMEAKKNVQTFLQQYHFGIFYSFIKLKQLEVRNIV 327

Human   330 WIAECISQRHRTKINSYIPI 349
            ||:|||:||...:||::|||
  Fly   328 WISECIAQRQTDRINAFIPI 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP6V0D2	NP_689778.1	vATP-synt_AC39	16..338	CDD:426553	131/323 (41%)
VhaAC39-2	NP_651128.1	vATP-synt_AC39	12..341	CDD:426553	133/328 (41%)