Protein Alignment Nefm and LamC

DIOPT Version :9

• Sequence 1: NP_058725.1
• Gene: Nefm / 24588
• RGDID: 3160
• Length: 845
• Species: Rattus norvegicus
• Sequence 2: NP_001260974.1
• Gene: LamC / 36615
• FlyBaseID: FBgn0010397
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 566
• Identity: 141/566 - (24%)
• Similarity: 229/566 - (40%)
• Gaps: 166/566 - (29%)

  Rat    15 RRVTETPSSFSRVSGSPSSGFRSQSWSRGSPSTVSSSYKRSALAPRLAYSSAMLSSAESSLDFSQ 79
            |||| ..:..||.|.|...|..|.|...|:.|..|.:
  Fly     4 RRVT-LNTRVSRASTSTPVGGASTSSRVGATSPTSPT---------------------------- 39

  Rat    80 SSSLLNGGSGGDYKLSRSNEKEQLQGLNDRFAGYIEKVHYLEQQNKEIEAEIHALRQKQASH--A 142
                         :.||..|||:||.||||.|.||:::..||.:|..:..|:: |.|...:.  :
  Fly    40 -------------RTSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELN-LAQDTVNRETS 90

  Rat   143 QLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKER--------------------- 186
            .|...|::|:...|..|:....|||::::|...|.|:...||.|
  Fly    91 NLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENR 155

  Rat   187 -----------------FEEEA--------RLR---DDTEAAIRALRKDIEESSMVKVELDKKVQ 223
                             ||::|        |||   ||       |||.:|..::.:|:|:.:.|
  Fly   156 YNEVNGKYNQSLADRKKFEDQAKELALENERLRRQLDD-------LRKQLEAETLARVDLENQNQ 213

  Rat   224 SLQDEVAFLRSNHEEEVADLLA--QIQASHITVERKDYLKTDISTALKEIRSQLECHSDQNMHQA 286
            ||::|:||....|.:|:.:..:  ||:.|.|........:..:..:|:|:|.|.|.....|..:.
  Fly   214 SLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEI 278

  Rat   287 EEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIE---- 347
            |..:......|..||.:..:....|.||:...|.::...:.:|:::..|...|..::.::|
  Fly   279 ELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLD 343

  Rat   348 ---ERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETR 409
               :|||..::|       ||.||:..:.|||..|:|||.|:::|::||:|||||.|||.|||.|
  Fly   344 TERQRHNQYIAS-------LEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERR 401

  Rat   410 F-------------------------STFSGSITGPLYTHRQPSVTISSKIQKTKVEAPKLKVQH 449
            .                         |:.||.:|........|.::.||.:::.:.
  Fly   402 LNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRRT--------- 457

  Rat   450 KFVEEIIEETKVEDEKSEMEDALTVIAEELAASAKEEKEEAEEKEE 495
                 :|:|:  ||.        |:....:.|:||.:.|..|...|
  Fly   458 -----VIDES--EDR--------TLSEYSVNAAAKGDLEIIEADVE 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nefm	NP_058725.1	Filament_head	10..97	CDD:282575	15/81 (19%)
		Filament	98..409	CDD:278467	106/370 (29%)
		Coil 1A	103..134		13/30 (43%)
		Linker 1	135..147		2/13 (15%)
		Coil 1B	148..246		35/148 (24%)
		Linker 12	247..263		3/15 (20%)
		Coil 2A	264..285		6/20 (30%)
		Linker 2	286..289		1/2 (50%)
		Coil 2B	290..410		41/126 (33%)
		Tail	411..844		18/85 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	482..782		5/14 (36%)
LamC	NP_001260974.1	Filament	45..401	CDD:278467	106/370 (29%)
		ATP-synt_B	<67..>142	CDD:304375	20/75 (27%)
		MreC	<178..>224	CDD:302802	17/52 (33%)
		LTD	473..574	CDD:279300	6/16 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910