DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ncam1 and DIP-iota

DIOPT Version :9

Sequence 1:XP_038936733.1 Gene:Ncam1 / 24586 RGDID:67378 Length:1136 Species:Rattus norvegicus
Sequence 2:NP_001097100.1 Gene:DIP-iota / 33925 FlyBaseID:FBgn0031837 Length:376 Species:Drosophila melanogaster


Alignment Length:297 Identity:82/297 - (27%)
Similarity:133/297 - (44%) Gaps:37/297 - (12%)


- Green bases have known domain annotations that are detailed below.


  Rat   220 IVNATANLGQSVTLVCDADGFPEPTMSWTK-DGEPIENEEED--DEKHIFSDDSSE-----LTIR 276
            |.|:|..:|:...|.|.........::|.: |.:.|.:.:..  .:.|..|...:|     |.||
  Fly    37 INNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISHTEHRIWQLKIR 101

  Rat   277 NVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMEL----EEQVTLTCEASGDPI 337
            :|.::|...|:|.......:.... :|.|...|.|  |:.||:.::    .:.|||||.|:|.|:
  Fly   102 DVQESDRGWYMCQINTDPMKSQMG-YLDVVVPPDI--VDYQTSQDVVRSTGQNVTLTCSATGVPM 163

  Rat   338 PSITWRTSTRNISSEEKASWTRPEKQETL---DGHMVVRSHARVSSLTLKSIQYTDAGEYICTAS 399
            |:||||               |.|....|   ||...|.| ....:|||..:|.:..|.|:|.||
  Fly   164 PTITWR---------------REEATPILISDDGDREVFS-VEGQNLTLWQVQRSHMGAYLCIAS 212

  Rat   400 NTIGQD-SQSMYLEVQYAPKLQGPV-AVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYS 462
            |.:... |:.:.|.|.:||.:.... .:|...|.::.:.|...:.|::...|.||.|||...:|.
  Fly   213 NGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPASVNFWLRDSQLLQGGSYE 277

  Rat   463 NIKIYNT-PSASYLEVTPDSENDFGNYNCTAVNRIGQ 498
            ::.:.:. .....:.:.|.::.|||.|.|.|.|.:||
  Fly   278 SVSVDHVFRIVMRITLRPITKRDFGEYICRAKNAMGQ 314

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ncam1XP_038936733.1 IgI_1_NCAM-1 20..116 CDD:409451
Ig strand B 37..41 CDD:409451
Ig strand C 51..55 CDD:409451
Ig strand E 79..83 CDD:409451
Ig strand F 93..98 CDD:409451
Ig strand G 107..110 CDD:409451
IG_like 124..190 CDD:214653
Ig strand B 135..139 CDD:409353
Ig strand C 148..152 CDD:409353
Ig strand E 172..176 CDD:409353
Ig strand F 186..191 CDD:409353
IgI_3_NCAM-1 211..308 CDD:143207 21/95 (22%)
Ig strand B 231..235 CDD:143207 1/3 (33%)
Ig strand C 244..248 CDD:143207 0/3 (0%)
Ig strand E 271..275 CDD:143207 2/8 (25%)
Ig strand F 285..290 CDD:143207 2/4 (50%)
Ig strand G 298..301 CDD:143207 0/2 (0%)
IgI_NCAM-1 307..413 CDD:143277 37/113 (33%)
Ig strand B 326..330 CDD:143277 3/3 (100%)
Ig strand C 339..343 CDD:143277 2/3 (67%)
Ig strand E 379..383 CDD:143277 1/3 (33%)
Ig strand F 393..398 CDD:143277 2/4 (50%)
Ig strand G 406..409 CDD:143277 1/2 (50%)
Ig_3 422..494 CDD:404760 18/73 (25%)
Ig strand B 433..437 CDD:409353 0/3 (0%)
Ig strand C 446..450 CDD:409353 0/3 (0%)
Ig strand E 473..477 CDD:409353 0/3 (0%)
Ig strand F 487..492 CDD:409353 2/4 (50%)
FN3 509..606 CDD:238020
fn3 619..701 CDD:394996
Herpes_BLLF1 <842..1133 CDD:282904
DIP-iotaNP_001097100.1 IG_like 39..125 CDD:214653 18/85 (21%)
Ig 39..122 CDD:299845 18/82 (22%)
Ig 132..213 CDD:299845 33/98 (34%)
IG_like 141..227 CDD:214653 32/101 (32%)
IG_like 239..322 CDD:214653 21/76 (28%)
IGc2 245..313 CDD:197706 18/67 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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