Protein Alignment Slco2a1 and Oatp58Db

DIOPT Version :9

• Sequence 1: NP_073158.2
• Gene: Slco2a1 / 24546
• RGDID: 3051
• Length: 644
• Species: Rattus norvegicus
• Sequence 2: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 169/636 - (26%)
• Similarity: 291/636 - (45%)
• Gaps: 99/636 - (15%)

  Rat    20 DRRCPRSV--------FSNIKVFVLCHGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSL 76
            |..|..|:        |:...:||:.:|:......:...||..::||:||||.:.:..||||:..
  Fly    32 DTTCGFSIFRGPALQRFATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKRFNIPTKISGLITVG 96

  Rat    77 NEISNATLIIFISYFGSRVNRPRMIGIGGLLLAAGAFVLTLPHF----------LSEPYQYTSTT 131
            |:||......|:||:.||.:|||.:.:|.:::|....::..||.          |:|.|
  Fly    97 NDISTVFSSAFLSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEY------ 155

  Rat   132 DGNRSSFQTDLCQKHLPALPPSKCHSTVPDTHKETSSLWG--------LMVVAQLLAGIGTVPIQ 188
             |...||...|   ::.....|.||      .|.::.|..        |..:||.:.|||.....
  Fly   156 -GMSESFGASL---NITEKNDSLCH------EKNSNCLERAGDYTPIVLFFIAQFIGGIGCSLFY 210

  Rat   189 PFGISYVDDFAEPTNSPLYISILFAIAVFGPAFGYLLGSVMLRIFVDYGRVDTATVNLSPGDPRW 253
            ..|:||:||.:..:.:|..:|....:.:.|||.|:.:.|:.||:::|..:....|.|    ||||
  Fly   211 APGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGFSMVSLCLRLYIDPFKKPLITTN----DPRW 271

  Rat   254 IGAWWLGLLISSGFLIVTSLPFFFFPRAMSRGAERSVTAEETMKTEED-----KSRGSLMDFIKR 313
            :||||:|.::.:..|.::::....||:.|.|...|.:.|:    .|||     :|...::|.:|
  Fly   272 MGAWWIGWILLTFILTISAVFVGMFPKEMPRAKARRLKAD----GEEDIPLAGRSFQDMLDSLK- 331

  Rat   314 FPRIFLRLLMNPLFMLVVLSQCTFSSVIAGLSTFLNKFLEKQYGATAAYANFLIGAVNLPAAALG 378
                  ||..|.:::..:|:...:.........|..|::|.||..:|:.:....|...|..:|.|
  Fly   332 ------RLASNKVYVYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAAG 390

  Rat   379 MLFGGILMKRFVFPLQTIPRVAAT------IITISMILCVPLFFMGCSTSAVAEVYPPSTSSSIH 437
            :|..|.::.::    :...|..|.      .:|::.:||..|  :||..|..|      .|.||.
  Fly   391 ILISGYVISKY----KPSARAMAAWNFVVDYLTVAGMLCYVL--VGCDESDRA------NSLSIV 443

  Rat   438 PQQPPACRRDCSCPDSFFHPVCGDNGVEYVSPCHAGCSSTNTSSEASKEPIYLNCSC-------- 494
            | ...:|...|.|...::.|||....:.::|.|||||  |:.:.....:.||..|.|
  Fly   444 P-TGDSCSASCVCEYVYYAPVCSPENITFISACHAGC--TDKAINELGKTIYTGCRCMGNVSSII 505

  Rat   495 -------VSGGSASAKTGSCPTSCAQLLLPSIFLISFAALIACISHNPLYMMVLRVVNQDEKSFA 552
                   ::..|..|..|:||..|.:..|..:.::.|...:.....:...::.||.|...:|:|:
  Fly   506 SLSNVTSLASQSQIAMDGACPVDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFS 570

  Rat   553 IGVQFLLMRLLAWLPAPSLYGLLIDSSCVRWNYLCSGRRGACAYYDNDALR 603
            :|...::..:||::|:|.::|.::||.|:.|...||. :|.|..||..:||
  Fly   571 LGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWGKTCSS-KGNCWIYDTKSLR 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slco2a1	NP_073158.2	oat	1..630	CDD:273279	169/636 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		169/636 (27%)
		MFS	<166..>425	CDD:119392	71/277 (26%)
		KAZAL_SLC21	442..496	CDD:238650	17/68 (25%)
Oatp58Db	NP_611658.3	OATP	53..619	CDD:281175	163/612 (27%)
		MFS	55..>410	CDD:119392	103/389 (26%)
		KAZAL_SLC21	447..499	CDD:238650	17/53 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339159
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850