DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ina and LamC

DIOPT Version :9

Sequence 1:NP_062001.2 Gene:Ina / 24503 RGDID:2911 Length:506 Species:Rattus norvegicus
Sequence 2:NP_001260974.1 Gene:LamC / 36615 FlyBaseID:FBgn0010397 Length:640 Species:Drosophila melanogaster


Alignment Length:513 Identity:138/513 - (26%)
Similarity:232/513 - (45%) Gaps:98/513 - (19%)


- Green bases have known domain annotations that are detailed below.


  Rat    44 SRSNVASTA----ACSSASSLGLGLAYRRLPASDGLDLSQAAARTNEYKIIRTNEKEQLQGLNDR 104
            :|.:.|||:    ..|::|.:|                  |.:.|:..:..|..|||:||.||||
  Fly    10 TRVSRASTSTPVGGASTSSRVG------------------ATSPTSPTRTSRQQEKEELQHLNDR 56

  Rat   105 FAVFIEKVHQLETQNRALEAELAALRQR-HAEPSRVGELFQRELRELRAQLEEASSARAQALLER 168
            .|.:|:::..||.:|..|..||...:.. :.|.|.:..::::||...|..|:|.:..:|:..::.
  Fly    57 LACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDI 121

  Rat   169 DGLAEEVQRLRARCEEESRGREGAE---------------------------------------- 193
            ..|.||...|:.|.:::::....||                                        
  Fly   122 KRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELALENER 186

  Rat   194 --RALKAQQRDVDGATLARLDLEKKVESLLDELAFVRQVHDEEVAELLATLQASSQAAAEVDVAV 256
              |.|...::.::..||||:|||.:.:||.:||||..|||.:|:.|..:..|..   .:|:|..:
  Fly   187 LRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIE---ISEIDGRL 248

  Rat   257 AK---PDLTSALREIRAQYESLAAKNLQSAEEWYKSKFANLNEQAARSTEAIRASREEIHEYRRQ 318
            ::   ..|..:|:|:|.|||.....|.:..|..|.::..||...|.|:.:....:.||:...|.:
  Fly   249 SRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTK 313

  Rat   319 LQARTIEIEGLRGANESLERQILELEERHSAEVAGYQDSIGQLESDLRNTKSEMARHLREYQDLL 383
            :.....:::.|...|..|..:|.|||.....|...:...|..||::|:..:.|||..|:|||.|:
  Fly   314 IDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLM 378

  Rat   384 NVKMALDIEIAAYRKLLEGEETRF---------STSGLSISGLNPLPNPSYLLPPRILSSTTSKV 439
            ::|::||:|||||.|||.|||.|.         :.||:|.:|       |:|...  .||.:.:|
  Fly   379 DIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNG-------SHLTAS--ASSRSGRV 434

  Rat   440 SSAGLSLKKEEEEEEEEEEEGASKEVTKKTSKVGESFEETLEE-TVVSTKKTEKSTIE 496
            :.:|        ..........|..|.::.:.:.||.:.||.| :|.:..|.:...||
  Fly   435 TPSG--------RRSATPGISGSSAVKRRRTVIDESEDRTLSEYSVNAAAKGDLEIIE 484

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
InaNP_062001.2 Head 1..87 9/46 (20%)
Filament_head 10..92 CDD:282575 9/51 (18%)
Coil 1A 88..129 18/40 (45%)
Filament 93..406 CDD:278467 106/358 (30%)
Linker 1 130..142 2/12 (17%)
Coil 1B 143..238 32/136 (24%)
Linker 2 239..262 3/25 (12%)
Coil 2 263..408 51/153 (33%)
LamCNP_001260974.1 Filament 45..401 CDD:278467 106/358 (30%)
ATP-synt_B <67..>142 CDD:304375 19/74 (26%)
MreC <178..>224 CDD:302802 15/45 (33%)
LTD 473..574 CDD:279300 3/12 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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