DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FRK and PIN3

DIOPT Version :9

Sequence 1:	NP_002022.1	Gene:	FRK / 2444	HGNCID:	3955	Length:	505	Species:	Homo sapiens
Sequence 2:	NP_015480.1	Gene:	PIN3 / 856277	SGDID:	S000006358	Length:	215	Species:	Saccharomyces cerevisiae

Alignment Length:	148	Identity:	37/148 - (25%)
Similarity:	59/148 - (39%)	Gaps:	37/148 - (25%)

- Green bases have known domain annotations that are detailed below.

Human     2 SNICQR-LWEYLEPYLPCLSTEADKSTVIENPGALCSPQSQRHGHYFVALFDYQARTAEDLSFRA 65
            ||:... :::.:...||   .:.|.:....|    .||.|.   .|..||:.:..:...||..:.
Yeast    23 SNVISNDVYDQINKSLP---AKWDPANAPRN----ASPASL---EYVEALYQFDPQQDGDLGLKP 77

Human    66 GDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVAEDRSLQAEPWFFGAIGRSD----- 125
            |||:|:|:.|...|:         .||.....|..|:|||        :|.|.|:.|.|:
Yeast    78 GDKVQLLEKLSPEWY---------KGSCNGRTGIFPANYV--------KPAFSGSNGPSNLPPPP 125

Human   126 ----AEKQLLYSENKTGS 139
                .|.|.:.::|...|
Yeast   126 QYKAQELQQIPTQNSAAS 143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FRK	NP_002022.1	SH3_Src_like	47..104	CDD:212779	15/56 (27%)
		SH2_Src_Frk	112..207	CDD:199831	9/37 (24%)
		PTKc_Frk_like	225..494	CDD:270653
PIN3	NP_015480.1	SH3	58..110	CDD:418401	19/68 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000