Protein Alignment Grik4 and Ir64a

DIOPT Version :9

• Sequence 1: NP_036704.1
• Gene: Grik4 / 24406
• RGDID: 2734
• Length: 956
• Species: Rattus norvegicus
• Sequence 2: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Alignment Length: 661
• Identity: 113/661 - (17%)
• Similarity: 212/661 - (32%)
• Gaps: 241/661 - (36%)

  Rat   340 IWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMDSRL 404
            :|..|   :||         .||:...                     :||.:...||:.:
  Fly   264 VWNPG---LNY---------GGHVNLT---------------------EIGSFTPTEGIQL---- 291

  Rat   405 YASNISDSLFNTTLVVTTILENPY----LMLKGNHQDMEGN-------------DRYEGFCVDML 452
                  .:.|.||..|...::..:    .|:...:::|.|.             |....|..::|
  Fly   292 ------HTWFRTTSTVRRRMDMQHARVRCMVVVTNKNMTGTLMYYLTHTMSGHIDTMNRFNFNLL 350

  Rat   453 KELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPF 517
            ..:.::  ||:...|.....:|..: ||.:.||:|.||..:.|:..|.:....||.|.||.:...
  Fly   351 MAVRDM--FNWTFVLSRTTSWGYVK-NGRFDGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRS 412

  Rat   518 MTLGISILYRVHMGRRPGYFSFLDPFSPGVWLFMLLAYLAVSC---VLFLVARLTPYEW-YSPH- 577
            .:.....::|.....:.....||.||:..||:      |.|.|   .:|::..||..|| ..||
  Fly   413 WSSRPCFIFRHPRSTQKDRIVFLQPFTNDVWI------LIVGCGVLTVFILWFLTTIEWKLVPHD 471

  Rat   578 --------------------------------------------------------PCAQG---- 582
                                                                    |...|
  Fly   472 GSALIKPKGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQ 536

  Rat   583 RCNLLVNQY-------------SLG---NSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLI 631
            ||...:|:|             .:|   .|:.|.||...|||...:...:|.||:......|:..
  Fly   537 RCYQKLNKYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFC 601

  Rat   632 IISSYTANLAAFLTVQRMEVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMW----- 691
            |...|:|::...|.:::.:. |:::.||. .::::.|......:..:|.:::......::
  Fly   602 IYQFYSASIVGTLLMEKPKT-IKTLSDLV-HSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKIT 664

  Rat   692 ------------------------------NYMYSKQPSVFVKST--------EEGIARVLNSNY 718
                                          :.::|.:.....|..        |.|:.|.|  .:
  Fly   665 SVPTTKENEADEDEPVDPNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLDPETGLLRHL--GF 727

  Rat   719 AF---------LLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENN 774
            ||         ::..|.:|   |..|:||::                |:|..:..::|:|.....
  Fly   728 AFHVDVAAAYKIIAETFSE---QDICDLTEV----------------SMFPPQKTVSIMQKNSPM 773

  Rat   775 RLEI---LKR-----------KWWEGGK--CPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMA 823
            |..|   |:|           ..|...|  |.|:.:.....:.|:.:....::|:....:.:.:.
  Fly   774 RKVISYGLRRVTETGILTYHFNVWHSRKPPCVKKIETSDLHVDMDTVSSALLILLFSYAITLMIL 838

  Rat   824 MLEFLWTLRHS 834
            ..|.|::..|:
  Fly   839 GTEILYSKWHN 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik4	NP_036704.1	Periplasmic_Binding_Protein_type1	24..402	CDD:415822	10/61 (16%)
		PBP2_iGluR_kainate_KA1	415..785	CDD:270442	93/533 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..956
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	31/122 (25%)
		Lig_chan	563..828	CDD:278489	47/287 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349673
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840