Protein Alignment Glra2 and Rdl

DIOPT Version :10

• Sequence 1: NP_036700.1
• Gene: Glra2 / 24397
• RGDID: 2705
• Length: 452
• Species: Rattus norvegicus
• Sequence 2: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 528
• Identity: 171/528 - (32%)
• Similarity: 251/528 - (47%)
• Gaps: 150/528 - (28%)

  Rat    58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD-DSLDLDP 121
            ||.|:|||:.||||.|...:::.|..|::|..||:.::.:.||.|.|.||||.:.|. ::|.:..
  Fly    70 YDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGS 134

  Rat   122 SMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTC 186
            ..:.:||.||.||.|||.:.||..||.|:.:|:..:|.:..|||||:|.||||:|:.||||.|.|
  Fly   135 EFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLC 199

  Rat   187 TMQLESFGYTMNDLIFEWLSDG--PVQVAEGLTLPQFILKEEKELGYCTK----HYNTGKFTCIE 245
            .:::|||||||.|:.:.| .||  .|.::..:.||||     :.||:..:    :..||.::.:.
  Fly   200 HIEIESFGYTMRDIRYFW-RDGLSSVGMSSEVELPQF-----RVLGHRQRATEINLTTGNYSRLA 258

  Rat   246 VKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPK 310
            .:....|.|||||||:||||.||||:||||||:|.:|.|||||||:||||||||..|.:.|:|||
  Fly   259 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPK 323

  Rat   311 VSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR----QHKEFLRLRRRQKRQNKEEDVTRESRFN 371
            :||||:||:::..|.:.|||:|||||.|.::::    :.:.|:.:::..:::.::.|...:.:.|
  Fly   324 ISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQAN 388

  Rat   372 FS-------------------------------------GYGMGH-------------------- 379
            .:                                     |:|.||
  Fly   389 PNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPI 453

  Rat   380 -------------C-----------LQVKD----------------------------------- 385
                         |           .:|.|
  Fly   454 GFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPP 518

  Rat   386 ----------------GTAVKATPANPL-PQPPKDADAIKKKFVDRAKRIDTISRAAFPLAFLIF 433
                            |....|.||:.| |...|....|.|........||..||..||:.|:.|
  Fly   519 GGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCF 583

  Rat   434 NIFYWITY 441
            |:.|||.|
  Fly   584 NLMYWIIY 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glra2	NP_036700.1	LIC	46..441	CDD:273305	170/526 (32%)
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	70/188 (37%)
		Cys-loop	185..199	CDD:349809	9/13 (69%)
		Neur_chan_memb	274..588	CDD:460753	80/313 (26%)