DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kirrel2 and CG34353

DIOPT Version :9

Sequence 1:NP_766486.1 Gene:Kirrel2 / 243911 MGIID:2442334 Length:700 Species:Mus musculus
Sequence 2:NP_001287571.1 Gene:CG34353 / 5740590 FlyBaseID:FBgn0085382 Length:581 Species:Drosophila melanogaster


Alignment Length:403 Identity:76/403 - (18%)
Similarity:127/403 - (31%) Gaps:129/403 - (32%)


- Green bases have known domain annotations that are detailed below.


Mouse    19 SSPHFLQQPEDMVVLLGEEARLPCALG---AYRGLVQWTKDGLAL---GGERDLPGWSRYWISGN 77
            :.|.|:.:.|....:.||...|||.:.   .|  :|.| |.|:|:   |..:..|......::| 
  Fly    84 NEPMFISRSETFKFITGETIVLPCEVANTDTY--VVAW-KRGIAILTAGSVKVTPDPRVRLVNG- 144

Mouse    78 SASGQHDLHIKPVELEDEASYECQASQAGLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGVPGNLT 142
                 .:|.|:.....|...|.||.:....|.....:.::|||....:..|..:.:..|....:.
  Fly   145 -----FNLQIRDALPTDAGDYICQIATMDPREITHTVEILVPPRIHHISTGGHLQVKKGSSVRIE 204

Mouse   143 CRSRGDSRPAPELLWFRDGIRLDGSSFHQTTLKDKATGTVENTLFLTPSSHDDGATLICRARSQA 207
            |.:.|:  |.|.:.|.|                                            ::..
  Fly   205 CSATGN--PMPNVTWSR--------------------------------------------KNNI 223

Mouse   208 LPTGRDTAVTLSLQYPPMVTLSAEPQTVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPR 272
            ||.|.:             .|.:...:::..::                  .|||..:       
  Fly   224 LPNGEE-------------KLHSHVLSIENVDR------------------HKGGVYI------- 250

Mouse   273 LEVVADATFLTEPVSCEVSNAVGS-ANRSTALEVLYGPILQAKPKSVSVDVGKDASFSCVWRGNP 336
                           |..:|.||. |:....|.||:.|.:..:...|....|.:|:..|:..|..
  Fly   251 ---------------CTANNRVGQPASSQVVLHVLFSPEISVERPVVFSGEGHEATLVCIVHGET 300

Mouse   337 LPRITW---------TRMGGSQVLSSGPTLRLPSVALEDAGDYVCRAEPRRTGLGGGKAQARLTV 392
            .|.:.|         |.....:...|..||.:..|..:|.|:|.|.||.:.     |||:..|.:
  Fly   301 QPEVIWFKDTMQLDTTERHIMETRGSRHTLIIRKVHPQDFGNYSCVAENQL-----GKARKTLQL 360

Mouse   393 NAPPVVTALQPAP 405
            :..|.|......|
  Fly   361 SGKPNVAVFNSPP 373

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kirrel2NP_766486.1 IG 27..116 CDD:214652 22/94 (23%)
Ig 122..220 CDD:416386 11/97 (11%)
Ig strand A 123..126 CDD:409353 0/2 (0%)
Ig strand A' 129..133 CDD:409353 0/3 (0%)
Ig strand B 140..147 CDD:409353 1/6 (17%)
Cell attachment site. /evidence=ECO:0000255 146..148 0/1 (0%)
Ig strand C 153..158 CDD:409353 1/4 (25%)
Ig strand C' 161..163 CDD:409353 0/1 (0%)
Ig strand D 166..173 CDD:409353 0/6 (0%)
Ig strand E 180..188 CDD:409353 0/7 (0%)
Ig strand F 197..205 CDD:409353 0/7 (0%)
Ig strand G 211..217 CDD:409353 1/5 (20%)
Ig_3 223..292 CDD:404760 5/68 (7%)
Ig strand B 241..245 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 0/3 (0%)
Ig strand E 272..275 CDD:409353 0/2 (0%)
Ig strand F 281..290 CDD:409353 1/8 (13%)
Ig strand G 298..301 CDD:409353 0/2 (0%)
Ig 315..392 CDD:416386 22/85 (26%)
Ig strand A' 316..321 CDD:409353 1/4 (25%)
Ig strand B 324..333 CDD:409353 2/8 (25%)
Ig strand C 339..343 CDD:409353 1/12 (8%)
Ig strand C' 346..348 CDD:409353 0/1 (0%)
Ig strand D 351..354 CDD:409353 0/2 (0%)
Ig strand E 355..360 CDD:409353 2/4 (50%)
Ig strand F 368..376 CDD:409353 4/7 (57%)
Ig strand G 382..392 CDD:409353 4/9 (44%)
Ig 394..498 CDD:416386 3/12 (25%)
Ig strand A 395..399 CDD:409353 1/3 (33%)
Ig strand A' 401..404 CDD:409353 0/2 (0%)
Ig strand B 412..419 CDD:409353
Ig strand C 426..431 CDD:409353
Ig strand C' 433..436 CDD:409353
Ig strand D 444..451 CDD:409353
Ig strand E 461..468 CDD:409353
Ig strand F 479..486 CDD:409353
Ig strand G 489..496 CDD:409353
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..576
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 671..700
CG34353NP_001287571.1 IG_like 100..180 CDD:214653 21/88 (24%)
Ig 103..177 CDD:143165 19/82 (23%)
IG_like 191..269 CDD:214653 20/176 (11%)
IGc2 198..258 CDD:197706 16/158 (10%)
I-set 273..360 CDD:254352 23/91 (25%)
Ig 290..359 CDD:143165 19/73 (26%)
FN3 <466..524 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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