DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kirrel2 and tutl

DIOPT Version :9

Sequence 1:NP_766486.1 Gene:Kirrel2 / 243911 MGIID:2442334 Length:700 Species:Mus musculus
Sequence 2:NP_001303307.1 Gene:tutl / 46015 FlyBaseID:FBgn0010473 Length:1536 Species:Drosophila melanogaster


Alignment Length:690 Identity:150/690 - (21%)
Similarity:237/690 - (34%) Gaps:197/690 - (28%)


- Green bases have known domain annotations that are detailed below.


Mouse    27 PEDMV---VLLGEEARLPCALG-------AYRGLVQWTKDGLALGGERDLPGWSRYW-------- 73
            |||.|   .:|||.....|.:.       .|  ::||.|.....|.:..:..|...:        
  Fly   132 PEDAVHITAILGEGVIFNCHVEFPNDHPVPY--VLQWDKKVSETGSDLPIYIWYESYPEHIEEGY 194

Mouse    74 ------ISGNSASGQHDLHIKPVELEDEASYECQASQAGLRSRPAQ--------LHVMVPPEAPQ 124
                  :|.:|..|...|::..:...|:..|||:.  ..|...|.|        |.|..||....
  Fly   195 KGRVSRVSQDSPFGSASLNLTNIRESDQGWYECKV--VFLNRDPKQHKNGTWFHLDVHAPPRFSV 257

Mouse   125 VLGGPSVSLVAGVPGNLTCRSRGDSRPAPELLWFRD----------GIRLDGSSFHQTTLKDKAT 179
            .   |...:...:..::....:.|..|.||:||::|          ||..||:....:|::    
  Fly   258 T---PEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIR---- 315

Mouse   180 GTVENTLFLTPSSHDDGATLICRARSQALPTGRDTAVTLS----LQYPPMVTLSAEPQTVQEGEK 240
                         |:|.....|.||:..........|.::    :..||      ..||..||||
  Fly   316 -------------HEDIGEYTCIARNGEGQVSHTARVIIAGGAVIMVPP------TNQTKLEGEK 361

Mouse   241 VTFLCQATAQPPVTGYRWAKGGSPV--LGARGPRLEVVADATFLTEPVS--------CEVSNAVG 295
            |.|.|:|.|.|.....||.:.||||  :.|...|:.:..|.:.:..|:.        |||:|.:|
  Fly   362 VIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIG 426

Mouse   296 SANRSTA-------LEVLYGPILQAKPKSVSVDVGKDASFSCVWRGNP-LPRITWTR-------- 344
            ....::|       .:|.:.|.:|..|..::..|      .|..:.:| |..:|||:        
  Fly   427 DPQSASAYLSVEYPAKVTFTPTVQYLPFRLAGVV------QCYIKSSPQLQYVTWTKDKRLLEPY 485

Mouse   345 -MGGSQVLSSGPTLRLPSVALEDAGDYVCRAEPRRTGLGGGKAQARLTVNAPPVVTALQPAPAFL 408
             |....|:::| :|....|..|..|.|.| ......|..|......:.|..||..| ::|...:.
  Fly   486 QMKDIVVMANG-SLLFTRVNEEHQGQYAC-TPYNAQGTAGASGVMDVLVRKPPAFT-VEPETLYQ 547

Mouse   409 RGPARLQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPEVEGGQGPGLISVLHISGTQE 473
            |            ...|||....|                  |.|.||.:.| .|......|.|.
  Fly   548 R------------KVGDSVEMHCD------------------ALEAEGTERP-TIKWQRQEGEQL 581

Mouse   474 SDFTTGFNCSARNR--LGEGRVQIHLGRRDLLPTVRIVAGAASAATSLLMVITGVVLCCWRHGSL 536
            ::       |.|||  :..|.:.|...||:.....:.|   .|...:.||.:|.:|:        
  Fly   582 TE-------SQRNRIKISGGNITIENLRREDFGYYQCV---VSNEVATLMAVTQLVI-------- 628

Mouse   537 SKQKNLVRIPGSSEGSSSRGPEEETGSSEDRGPIVHTDHSDLVLE----EKEALETKDPTNGYYR 597
                         ||:....|...||.:.:         |.:.|:    .....|.|.....::|
  Fly   629 -------------EGTQPHAPYNITGKATE---------SSITLQWLPGYSGGSEYKQDYTIWFR 671

Mouse   598 VRGVSVSLSLGEAPGGGLFLPPPSPIGLPG--TPTYYDFK 635
            ..||:...::...|.|.      :.:.:.|  :.|.|:|:
  Fly   672 EAGVNDWQTISVTPSGS------TQVTINGLASGTTYEFQ 705

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kirrel2NP_766486.1 IG 27..116 CDD:214652 26/120 (22%)
Ig 122..220 CDD:416386 19/111 (17%)
Ig strand A 123..126 CDD:409353 0/2 (0%)
Ig strand A' 129..133 CDD:409353 1/3 (33%)
Ig strand B 140..147 CDD:409353 0/6 (0%)
Cell attachment site. /evidence=ECO:0000255 146..148 0/1 (0%)
Ig strand C 153..158 CDD:409353 3/4 (75%)
Ig strand C' 161..163 CDD:409353 1/1 (100%)
Ig strand D 166..173 CDD:409353 1/6 (17%)
Ig strand E 180..188 CDD:409353 0/7 (0%)
Ig strand F 197..205 CDD:409353 2/7 (29%)
Ig strand G 211..217 CDD:409353 0/5 (0%)
Ig_3 223..292 CDD:404760 27/78 (35%)
Ig strand B 241..245 CDD:409353 2/3 (67%)
Ig strand C 255..259 CDD:409353 1/3 (33%)
Ig strand E 272..275 CDD:409353 1/2 (50%)
Ig strand F 281..290 CDD:409353 2/16 (13%)
Ig strand G 298..301 CDD:409353 0/2 (0%)
Ig 315..392 CDD:416386 19/86 (22%)
Ig strand A' 316..321 CDD:409353 0/4 (0%)
Ig strand B 324..333 CDD:409353 1/8 (13%)
Ig strand C 339..343 CDD:409353 1/3 (33%)
Ig strand C' 346..348 CDD:409353 0/1 (0%)
Ig strand D 351..354 CDD:409353 0/2 (0%)
Ig strand E 355..360 CDD:409353 1/4 (25%)
Ig strand F 368..376 CDD:409353 3/7 (43%)
Ig strand G 382..392 CDD:409353 1/9 (11%)
Ig 394..498 CDD:416386 23/105 (22%)
Ig strand A 395..399 CDD:409353 2/3 (67%)
Ig strand A' 401..404 CDD:409353 0/2 (0%)
Ig strand B 412..419 CDD:409353 0/6 (0%)
Ig strand C 426..431 CDD:409353 2/4 (50%)
Ig strand C' 433..436 CDD:409353 0/2 (0%)
Ig strand D 444..451 CDD:409353 0/6 (0%)
Ig strand E 461..468 CDD:409353 1/6 (17%)
Ig strand F 479..486 CDD:409353 1/6 (17%)
Ig strand G 489..496 CDD:409353 1/6 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..576 5/33 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 671..700
tutlNP_001303307.1 V-set 137..250 CDD:284989 22/116 (19%)
IG_like 137..229 CDD:214653 18/93 (19%)
I-set 253..341 CDD:254352 20/107 (19%)
IGc2 268..331 CDD:197706 17/79 (22%)
I-set 346..437 CDD:254352 30/96 (31%)
Ig 349..437 CDD:299845 30/93 (32%)
Ig 459..530 CDD:299845 18/78 (23%)
IG_like 549..628 CDD:214653 25/107 (23%)
IGc2 551..617 CDD:197706 22/94 (23%)
FN3 633..725 CDD:238020 16/88 (18%)
FN3 786..874 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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