DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kirrel2 and Dscam3

DIOPT Version :9

Sequence 1:NP_766486.1 Gene:Kirrel2 / 243911 MGIID:2442334 Length:700 Species:Mus musculus
Sequence 2:NP_996226.2 Gene:Dscam3 / 42103 FlyBaseID:FBgn0261046 Length:2087 Species:Drosophila melanogaster


Alignment Length:626 Identity:132/626 - (21%)
Similarity:223/626 - (35%) Gaps:147/626 - (23%)


- Green bases have known domain annotations that are detailed below.


Mouse    74 ISGNSASGQHDLHIKPVELEDEASYECQASQA-GLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGV 137
            :||:..|..:..|::|   :|...|:|.||.: |.....|:|:|..||....:  || :..|||.
  Fly   496 MSGDVISHLNISHVRP---DDGGLYKCVASNSMGSVQHSAR
LNVYGPPYVRAI--GP-IKAVAGE 554

Mouse   138 PGNLTCRSRGDSRPAPELLWFRDGIRLDGSSFHQTTLKDKATGTVENTLFLTPSSH------DDG 196
            ...:.|...|  .|..::.|         ...||.               ||.|:|      .||
  Fly   555 DIIVHCPFAG--YPVEQIRW---------EKAHQE---------------LTTSNHYELASVADG 593

Mouse   197 ATLI--------------CRARSQALPTGRDTAVTLSLQYPPMVTLSAEPQTVQEGEKVTFLCQA 247
            ..|:              |..||:|....| ..:.|::..||::.....|:.:|||.:....|..
  Fly   594 GQLVIKNVEPGRDQGIYTCIVRSRAG
EEAR-RDMQLNVNSPPVIEPFKFPKNLQEGGRAQITCAV 657

Mouse   248 TAQPPVTGYRWAKGGSPVLGARGPRLEVVAD-----ATFLTEPVS--------CEVSNAVGSANR 299
            ::......:.|.|..|.:..:    |::...     :..:.:.:|        |..|||....|.
  Fly   658 SSGDMPIYFSWKKDDSSIPSS----LQITEKKEEFYSLLVFKDISARHSGKYTCYASNAAAKVNY 718

Mouse   300 STALEVLYGPILQAKPKSVSVDVGKDASFSCVWRGNPLPRITWTRMGGSQVLSSGP-TLRLPSVA 363
            :..|:|...|..:.:|...::.:|...|.:|...|.|:|.|||.:..|.......| ::|..|:.
  Fly   719 TAELQV
RVAPRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKGQGKGSKDFKPLSMRNHSLL 783

Mouse   364 L-----EDAGDYVCRAEPRRTGLGGG-KAQARLTVNAPP-VVTALQPAPAFLRGPARLQCVVFAS 421
            |     .|.|.|:|:|   ...:|.| |...|:.||.|. ...:.:...:....|..|.|.. ..
  Fly   784 LNLATDNDEGYYMCQA---TNEIGAGLKKTIRINV
NEPARFEQSARNISSRRNDPVTLDCHA-KG 844

Mouse   422 PAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPEVEGGQGPGLISVLHISGTQESDFTTG-FNCSAR 485
            ..|.::.|:.:.|.::..:. ||.:......:       |:.|.|.|..:...|  :| :.|.|.
  Fly   845 DEPITIGWTQNNGRIDLNNF-RFSIAEMKTEK-------GVDSQLTIGHSDRHD--SGVYRCIAE 899

Mouse   486 NRLGEGRVQIHLGRRDLLPTVRIVAGAASAATSLLMVITGVVLCCWR------------------ 532
            |..|.....|.|..::...|        .:...:..|.:..|...||                  
  Fly   900 NPYGRAEQIIFLAVQERPDT--------PSHLEIFEVGSRTVKLSWRRPFDGNSPVLSYLVQYQA 956

Mouse   533 ------HGSLSKQKN-------LVRIPGSSEGSSSRGPEEETGSSEDRGP-------------IV 571
                  ||||:....       .|.:|.:|...|......|:.......|             |.
  Fly   957 LKYLQSHGSLAAAGGDWNGHVINVSLPSTSISRSYDSDLRESAIVAGLTPATTFLIRMQAINEIE 1021

Mouse   572 HTDHSD-LVLEEKEALETKDPTNGYYRVRGVSVSLSLGEAP 611
            .:.::: :||:.:|...|:.|:|...:..|.|..:...:.|
  Fly  1022 RSAYTEAIVLKTQEEAPTEAPSNVQVQTGGESELIVTWQIP 1062

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kirrel2NP_766486.1 IG 27..116 CDD:214652 13/42 (31%)
Ig 122..220 CDD:416386 24/117 (21%)
Ig strand A 123..126 CDD:409353 0/2 (0%)
Ig strand A' 129..133 CDD:409353 1/3 (33%)
Ig strand B 140..147 CDD:409353 1/6 (17%)
Cell attachment site. /evidence=ECO:0000255 146..148 0/1 (0%)
Ig strand C 153..158 CDD:409353 0/4 (0%)
Ig strand C' 161..163 CDD:409353 0/1 (0%)
Ig strand D 166..173 CDD:409353 2/6 (33%)
Ig strand E 180..188 CDD:409353 0/7 (0%)
Ig strand F 197..205 CDD:409353 2/21 (10%)
Ig strand G 211..217 CDD:409353 1/5 (20%)
Ig_3 223..292 CDD:404760 13/81 (16%)
Ig strand B 241..245 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 0/3 (0%)
Ig strand E 272..275 CDD:409353 1/2 (50%)
Ig strand F 281..290 CDD:409353 2/16 (13%)
Ig strand G 298..301 CDD:409353 1/2 (50%)
Ig 315..392 CDD:416386 24/83 (29%)
Ig strand A' 316..321 CDD:409353 0/4 (0%)
Ig strand B 324..333 CDD:409353 2/8 (25%)
Ig strand C 339..343 CDD:409353 2/3 (67%)
Ig strand C' 346..348 CDD:409353 0/1 (0%)
Ig strand D 351..354 CDD:409353 0/2 (0%)
Ig strand E 355..360 CDD:409353 2/5 (40%)
Ig strand F 368..376 CDD:409353 4/7 (57%)
Ig strand G 382..392 CDD:409353 4/10 (40%)
Ig 394..498 CDD:416386 20/105 (19%)
Ig strand A 395..399 CDD:409353 1/4 (25%)
Ig strand A' 401..404 CDD:409353 0/2 (0%)
Ig strand B 412..419 CDD:409353 2/6 (33%)
Ig strand C 426..431 CDD:409353 1/4 (25%)
Ig strand C' 433..436 CDD:409353 1/2 (50%)
Ig strand D 444..451 CDD:409353 1/6 (17%)
Ig strand E 461..468 CDD:409353 3/6 (50%)
Ig strand F 479..486 CDD:409353 3/7 (43%)
Ig strand G 489..496 CDD:409353 1/6 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..576 7/46 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 671..700
Dscam3NP_996226.2 IG 56..133 CDD:214652
Ig 56..125 CDD:143165
I-set 246..337 CDD:254352
Ig 264..334 CDD:143165
I-set 345..433 CDD:254352
Ig 358..431 CDD:143165
Ig 456..533 CDD:143165 11/39 (28%)
IGc2 553..619 CDD:197706 17/91 (19%)
I-set 634..724 CDD:254352 17/93 (18%)
ig 645..712 CDD:278476 11/70 (16%)
IG_like 734..815 CDD:214653 24/83 (29%)
Ig 745..815 CDD:299845 22/72 (31%)
I-set 820..913 CDD:254352 20/103 (19%)
Ig 838..920 CDD:299845 20/100 (20%)
FN3 917..1033 CDD:238020 18/123 (15%)
FN3 1040..1142 CDD:238020 5/23 (22%)
fn3 1150..1237 CDD:278470
FN3 1263..1345 CDD:238020
Ig 1350..1436 CDD:299845
IG_like 1358..1436 CDD:214653
FN3 1441..1530 CDD:238020
FN3 1542..1620 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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