DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Kirrel2 and dpr16

DIOPT Version :9

Sequence 1:	NP_766486.1	Gene:	Kirrel2 / 243911	MGIID:	2442334	Length:	700	Species:	Mus musculus
Sequence 2:	NP_001287169.1	Gene:	dpr16 / 40619	FlyBaseID:	FBgn0037295	Length:	488	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	65/294 - (22%)
Similarity:	95/294 - (32%)	Gaps:	102/294 - (34%)

- Green bases have known domain annotations that are detailed below.

Mouse    27 PEDMVVLLGEEARLPCALGAYRGL-VQW-----------------------------TKDGLALG 61
            |.:..|..|:.|.|||.|..:.|. :.|                             |...|..|
  Fly   205 PLNATVQAGQHAYLPCKLNQHSGKPLSWVRLRDEHIIAVDHTTFINDARFASLLQSTTLTTLVSG 269

Mouse    62 G----------------ERDLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQASQAGLRSR 110
            |                ...:||...   .|||:|....|.||.|.|||...||||.:.....|.
  Fly   270 GALSTTATPVAALGNSFAHAVPGGQE---RGNSSSLSWTLQIKYVNLEDAGWYECQLATEPKMSA 331

Mouse   111 PAQLHVMVPPEAPQVLGGPSVSLVAGVPGNLTCRSRGDSRPAPELLWFRDGIRLDGSSFHQTTLK 175
            ..||.|:.|  ..:::|.....:.||....|.|..||.......:.|:|..        .|.|.:
  Fly   332 KVQLFVITP--RTELIGDRQRFVKAGSRVELHCIVRGTLEAPKYIFWYRGD--------QQVTAE 386

Mouse   176 DKATGT-------VENTLFLTPSSHDDGATLICRARSQALPTGRDTAVTLSLQYPPMV------T 227
            ::|:|.       ::..:|        |:|          ...|:|..:|.:   |:|      .
  Fly   387 NEASGAQSGWYTQIDRNIF--------GST----------EHNRNTIGSLVI---PLVRKIHSGN 430

Mouse   228 LSAEPQT---------VQEGEKVTFLCQATAQPP 252
            .:.||:.         |..||......::||..|
  Fly   431 YTCEPENSAAASMQLHVLSGEYSASAIKSTAARP 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kirrel2	NP_766486.1	IG	27..116	CDD:214652	34/134 (25%)
		Ig	122..220	CDD:416386	19/104 (18%)
		Ig strand A	123..126	CDD:409353	0/2 (0%)
		Ig strand A'	129..133	CDD:409353	0/3 (0%)
		Ig strand B	140..147	CDD:409353	2/6 (33%)
		Cell attachment site. /evidence=ECO:0000255	146..148		1/1 (100%)
		Ig strand C	153..158	CDD:409353	0/4 (0%)
		Ig strand C'	161..163	CDD:409353	0/1 (0%)
		Ig strand D	166..173	CDD:409353	1/6 (17%)
		Ig strand E	180..188	CDD:409353	1/14 (7%)
		Ig strand F	197..205	CDD:409353	1/7 (14%)
		Ig strand G	211..217	CDD:409353	2/5 (40%)
		Ig_3	223..292	CDD:404760	10/45 (22%)
		Ig strand B	241..245	CDD:409353	0/3 (0%)
		Ig strand C	255..259	CDD:409353
		Ig strand E	272..275	CDD:409353
		Ig strand F	281..290	CDD:409353
		Ig strand G	298..301	CDD:409353
		Ig	315..392	CDD:416386
		Ig strand A'	316..321	CDD:409353
		Ig strand B	324..333	CDD:409353
		Ig strand C	339..343	CDD:409353
		Ig strand C'	346..348	CDD:409353
		Ig strand D	351..354	CDD:409353
		Ig strand E	355..360	CDD:409353
		Ig strand F	368..376	CDD:409353
		Ig strand G	382..392	CDD:409353
		Ig	394..498	CDD:416386
		Ig strand A	395..399	CDD:409353
		Ig strand A'	401..404	CDD:409353
		Ig strand B	412..419	CDD:409353
		Ig strand C	426..431	CDD:409353
		Ig strand C'	433..436	CDD:409353
		Ig strand D	444..451	CDD:409353
		Ig strand E	461..468	CDD:409353
		Ig strand F	479..486	CDD:409353
		Ig strand G	489..496	CDD:409353
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	542..576
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	671..700
dpr16	NP_001287169.1	IG_like	205..337	CDD:214653	34/134 (25%)
		Ig	<298..338	CDD:299845	17/39 (44%)
		IG_like	352..447	CDD:214653	22/123 (18%)
		Ig	358..439	CDD:143165	20/109 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900