DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Kirrel2 and dpr20

DIOPT Version :9

Sequence 1:NP_766486.1 Gene:Kirrel2 / 243911 MGIID:2442334 Length:700 Species:Mus musculus
Sequence 2:NP_612066.1 Gene:dpr20 / 38101 FlyBaseID:FBgn0035170 Length:525 Species:Drosophila melanogaster


Alignment Length:213 Identity:50/213 - (23%)
Similarity:73/213 - (34%) Gaps:41/213 - (19%)


- Green bases have known domain annotations that are detailed below.


Mouse    21 PHF-----LQQPEDMVVLLGEEARLPCALGAYRG-LVQWTK-----DGLALGGERDL-------- 66
            |||     :.|..::.|..|....|.|.:...:. .|.|.:     :|...|...||        
  Fly   265 PHFEDVQRIGQATNLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTY 329

Mouse    67 PGWSRYWISGNSASGQHDLHIKPVELEDEASYECQASQAGLRSRPAQLHVMVPPEAPQVL----- 126
            .|..||.:.....:... |.|..|:.:|||.||||.|....|.....|||    .||:|:     
  Fly   330 TGDKRYKMEFQYPNNWR-LKITNVKKDDEAIYECQISTHPPRVIQINLHV----NAPKVMIVDEV 389

Mouse   127 GGPSVSLVAGVPG--NLTCRSRGDSRPAPELLW------FRDGIRLDGSSFHQTTLKDKATGTVE 183
            |.|.......:..  .|:|..|..:..:..:.|      ....:...|.|.....::|.|    .
  Fly   390 GDPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWKHMDNILNYDVTRGGVSVKTELMEDGA----N 450

Mouse   184 NTLFLTPSSHDDGATLIC 201
            :||.:...|..|.....|
  Fly   451 STLSIAKISKTDSGNYTC 468

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kirrel2NP_766486.1 IG 27..116 CDD:214652 26/102 (25%)
Ig 122..220 CDD:416386 18/93 (19%)
Ig strand A 123..126 CDD:409353 1/2 (50%)
Ig strand A' 129..133 CDD:409353 1/3 (33%)
Ig strand B 140..147 CDD:409353 2/6 (33%)
Cell attachment site. /evidence=ECO:0000255 146..148 1/1 (100%)
Ig strand C 153..158 CDD:409353 1/10 (10%)
Ig strand C' 161..163 CDD:409353 0/1 (0%)
Ig strand D 166..173 CDD:409353 2/6 (33%)
Ig strand E 180..188 CDD:409353 2/7 (29%)
Ig strand F 197..205 CDD:409353 1/5 (20%)
Ig strand G 211..217 CDD:409353
Ig_3 223..292 CDD:404760
Ig strand B 241..245 CDD:409353
Ig strand C 255..259 CDD:409353
Ig strand E 272..275 CDD:409353
Ig strand F 281..290 CDD:409353
Ig strand G 298..301 CDD:409353
Ig 315..392 CDD:416386
Ig strand A' 316..321 CDD:409353
Ig strand B 324..333 CDD:409353
Ig strand C 339..343 CDD:409353
Ig strand C' 346..348 CDD:409353
Ig strand D 351..354 CDD:409353
Ig strand E 355..360 CDD:409353
Ig strand F 368..376 CDD:409353
Ig strand G 382..392 CDD:409353
Ig 394..498 CDD:416386
Ig strand A 395..399 CDD:409353
Ig strand A' 401..404 CDD:409353
Ig strand B 412..419 CDD:409353
Ig strand C 426..431 CDD:409353
Ig strand C' 433..436 CDD:409353
Ig strand D 444..451 CDD:409353
Ig strand E 461..468 CDD:409353
Ig strand F 479..486 CDD:409353
Ig strand G 489..496 CDD:409353
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..576
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 671..700
dpr20NP_612066.1 IG_like 278..365 CDD:214653 23/87 (26%)
Ig 279..378 CDD:299845 26/99 (26%)
Ig 400..471 CDD:299845 13/73 (18%)
IG_like 402..480 CDD:214653 13/71 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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