DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kirrel2 and wrapper

DIOPT Version :9

Sequence 1:NP_766486.1 Gene:Kirrel2 / 243911 MGIID:2442334 Length:700 Species:Mus musculus
Sequence 2:NP_477404.1 Gene:wrapper / 37555 FlyBaseID:FBgn0025878 Length:500 Species:Drosophila melanogaster


Alignment Length:394 Identity:91/394 - (23%)
Similarity:145/394 - (36%) Gaps:76/394 - (19%)


- Green bases have known domain annotations that are detailed below.


Mouse    13 FKGHAGSSPHFLQQPEDMVVLLGEEARLPCALGAYRGLVQWTKDGLALGGER--DLPGWSR--YW 73
            |.....:|..|...|..:.....:..:|||.|......|:|.:|.:||...|  :||...|  .|
  Fly    27 FNNDLENSQKFKSIPTTVKTYENDTVQLPCTLNTPFRYVRWHRDDVALVDSRHPELPPPDRIMLW 91

Mouse    74 ISGNSASGQHDLHIKPVELEDEASYECQA-SQAGLRSRPAQLHVMVPPEAPQVLGGPS--VSLVA 135
            .:|:       |.:..|:..|...|.|:. |.:|   ...|.|.:....|||||..||  .....
  Fly    92 PNGS-------LQVANVQSSDTGDYYCEMNSDSG---HVVQQHAIEVQLAPQVLIEPSDLTEQRI 146

Mouse   136 GVPGNLTCRSRGDSRPAPELLWFRDGIRLDGSSFHQTTLKDKATGTVENTLFLTPSSHDDGATLI 200
            |....:.|.::|  .|.|.:.|     ||:|:     .::.::......:|.|...|.:....:.
  Fly   147 GAIFEVVCEAQG--VPQPVITW-----RLNGN-----VIQPQSNTGNRQSLILEIKSRNQAGLIE 199

Mouse   201 CRARSQALPTGRDTAVTLSLQYPPMVTLSAEPQTV---QEGEKVTFLCQATAQPPVTGYRWAKGG 262
            |.| |..:.......|.|.:.:.|.|::   ||.|   :.|.:....|...|.|..| .:|...|
  Fly   200 CVA-SNGVGEPAVANVYLHVLFSPEVSI---PQPVVYTKLGSRAHLECIVEAAPAAT-VKWFHHG 259

Mouse   263 SPV-LGARG----PRLEVVADATFLTEPV-----------------SCEVSNAVGSANRSTALEV 305
            .|| |||..    ..|:...........|                 .|..||.:  :.:|.::|:
  Fly   260 LPVALGAHSTTHESELQTNRSVDHYVNAVRHMLVVKSVRNADMGQYECRASNQI--SVKSGSVEL 322

Mouse   306 LYGPILQAKPKSVSVDVGKDASFS--CVWRGNPLPRITWTRMGGSQVLSSGPT---------LRL 359
            ...|:    |....::.|..:|.|  .||:...|..|...::...|:.|:..|         |.:
  Fly   323 TGRPM----PCLFKINPGTQSSTSHVLVWQTESLLPIMEFKLKFRQIPSNNVTRQVRTNWTELTI 383

Mouse   360 PSVA 363
            |:.|
  Fly   384 PAQA 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kirrel2NP_766486.1 IG 27..116 CDD:214652 24/93 (26%)
Ig 122..220 CDD:416386 24/99 (24%)
Ig strand A 123..126 CDD:409353 2/2 (100%)
Ig strand A' 129..133 CDD:409353 2/5 (40%)
Ig strand B 140..147 CDD:409353 1/6 (17%)
Cell attachment site. /evidence=ECO:0000255 146..148 0/1 (0%)
Ig strand C 153..158 CDD:409353 1/4 (25%)
Ig strand C' 161..163 CDD:409353 0/1 (0%)
Ig strand D 166..173 CDD:409353 1/6 (17%)
Ig strand E 180..188 CDD:409353 1/7 (14%)
Ig strand F 197..205 CDD:409353 2/7 (29%)
Ig strand G 211..217 CDD:409353 0/5 (0%)
Ig_3 223..292 CDD:404760 20/93 (22%)
Ig strand B 241..245 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 0/3 (0%)
Ig strand E 272..275 CDD:409353 1/2 (50%)
Ig strand F 281..290 CDD:409353 2/25 (8%)
Ig strand G 298..301 CDD:409353 0/2 (0%)
Ig 315..392 CDD:416386 14/60 (23%)
Ig strand A' 316..321 CDD:409353 0/4 (0%)
Ig strand B 324..333 CDD:409353 3/10 (30%)
Ig strand C 339..343 CDD:409353 1/3 (33%)
Ig strand C' 346..348 CDD:409353 0/1 (0%)
Ig strand D 351..354 CDD:409353 1/2 (50%)
Ig strand E 355..360 CDD:409353 2/13 (15%)
Ig strand F 368..376 CDD:409353
Ig strand G 382..392 CDD:409353
Ig 394..498 CDD:416386
Ig strand A 395..399 CDD:409353
Ig strand A' 401..404 CDD:409353
Ig strand B 412..419 CDD:409353
Ig strand C 426..431 CDD:409353
Ig strand C' 433..436 CDD:409353
Ig strand D 444..451 CDD:409353
Ig strand E 461..468 CDD:409353
Ig strand F 479..486 CDD:409353
Ig strand G 489..496 CDD:409353
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..576
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 671..700
wrapperNP_477404.1 Ig 41..124 CDD:299845 24/92 (26%)
IG_like 41..118 CDD:214653 22/83 (27%)
IG_like 145..218 CDD:214653 17/85 (20%)
Ig 147..219 CDD:299845 17/84 (20%)
I-set 224..323 CDD:254352 23/104 (22%)
IGc2 236..314 CDD:197706 17/80 (21%)
FN3 339..431 CDD:238020 12/49 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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