DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kirrel2 and Lac

DIOPT Version :9

Sequence 1:NP_766486.1 Gene:Kirrel2 / 243911 MGIID:2442334 Length:700 Species:Mus musculus
Sequence 2:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster


Alignment Length:386 Identity:93/386 - (24%)
Similarity:142/386 - (36%) Gaps:106/386 - (27%)


- Green bases have known domain annotations that are detailed below.


Mouse   171 QTTLKDKATGTVE-----------NTLFLTPSSH----DDGATLICRARSQALPTGRDTAVTLSL 220
            |..:|| ..||||           |.|||...|.    ..|:||:.          :|:  ..||
  Fly    36 QEQIKD-IGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVI----------KDS--RFSL 87

Mouse   221 QYPP-MVTLSAEPQTVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADATFLTE 284
            :|.| ..|...:.:.:||.:..|:.||....                               ...
  Fly    88 RYDPNSSTYKLQIKDIQETDAGTYTCQVVIS-------------------------------TVH 121

Mouse   285 PVSCEVSNAVGSANRSTALEVLYGPIL-QAKPKSVSVDVGKDASFSCVWRGNPLPRITWTRMGGS 348
            .||.||.           |.|...|:: ....:||....|.:....|...|.|.|.|||.|...:
  Fly   122 KVSAEVK-----------LSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNA 175

Mouse   349 QVLSS------GPTLRLPSVALEDAGDYVCRAEPRRTGLG-GGKAQARLTVNAPPVVTALQPAPA 406
             :|.:      |.|||:.||..||.|.|.|.|:   .|:. |.:....:.|...||:|.  |.|.
  Fly   176 -ILPTDSATYVGNTLRIKSVKKEDRGTYYCVAD---NGVSKGDRRNINVEVEFAPVITV--PRPR 234

Mouse   407 F---LRGPARLQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPEVEGGQGPGLISVLHI 468
            .   |:....|:|.:.|.| |.::||:.|:  ::..:...:.:..|...:   ......:.|:.:
  Fly   235 LGQALQYDMDLECHIEAYP-PPAIVWTKDD--IQLANNQHYSISHFATAD---EYTDSTLRVITV 293

Mouse   469 SGTQESDFTTGFNCSARNRLGEGRVQIHLGRRDLLPTV------RIVAGAAS-AATSLLMV 522
            ...|..|:.    |.|.||.||...:::| ...::|..      ..:|||.. :|||..:|
  Fly   294 EKRQYGDYV----CKATNRFGEAEARVNL-FETIIPVCPPACGQAYIAGAEDVSATSFALV 349

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kirrel2NP_766486.1 IG 27..116 CDD:214652
Ig 122..220 CDD:416386 16/63 (25%)
Ig strand A 123..126 CDD:409353
Ig strand A' 129..133 CDD:409353
Ig strand B 140..147 CDD:409353
Cell attachment site. /evidence=ECO:0000255 146..148
Ig strand C 153..158 CDD:409353
Ig strand C' 161..163 CDD:409353
Ig strand D 166..173 CDD:409353 1/1 (100%)
Ig strand E 180..188 CDD:409353 6/18 (33%)
Ig strand F 197..205 CDD:409353 2/7 (29%)
Ig strand G 211..217 CDD:409353 1/5 (20%)
Ig_3 223..292 CDD:404760 11/69 (16%)
Ig strand B 241..245 CDD:409353 1/3 (33%)
Ig strand C 255..259 CDD:409353 0/3 (0%)
Ig strand E 272..275 CDD:409353 0/2 (0%)
Ig strand F 281..290 CDD:409353 2/8 (25%)
Ig strand G 298..301 CDD:409353 0/2 (0%)
Ig 315..392 CDD:416386 26/83 (31%)
Ig strand A' 316..321 CDD:409353 2/4 (50%)
Ig strand B 324..333 CDD:409353 1/8 (13%)
Ig strand C 339..343 CDD:409353 2/3 (67%)
Ig strand C' 346..348 CDD:409353 0/1 (0%)
Ig strand D 351..354 CDD:409353 1/8 (13%)
Ig strand E 355..360 CDD:409353 3/4 (75%)
Ig strand F 368..376 CDD:409353 4/7 (57%)
Ig strand G 382..392 CDD:409353 1/10 (10%)
Ig 394..498 CDD:416386 24/106 (23%)
Ig strand A 395..399 CDD:409353 2/3 (67%)
Ig strand A' 401..404 CDD:409353 0/2 (0%)
Ig strand B 412..419 CDD:409353 2/6 (33%)
Ig strand C 426..431 CDD:409353 2/4 (50%)
Ig strand C' 433..436 CDD:409353 0/2 (0%)
Ig strand D 444..451 CDD:409353 1/6 (17%)
Ig strand E 461..468 CDD:409353 1/6 (17%)
Ig strand F 479..486 CDD:409353 2/6 (33%)
Ig strand G 489..496 CDD:409353 2/6 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..576
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 671..700
LacNP_523713.2 IG_like 36..131 CDD:214653 31/149 (21%)
FR1 37..50 CDD:409353 6/13 (46%)
Ig strand A' 37..42 CDD:409353 2/5 (40%)
Ig strand B 44..51 CDD:409353 4/6 (67%)
CDR1 51..59 CDD:409353 0/7 (0%)
Ig strand C 59..63 CDD:409353 2/3 (67%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 4/23 (17%)
Ig strand C' 68..72 CDD:409353 0/3 (0%)
Ig strand C' 79..81 CDD:409353 0/11 (0%)
FR3 84..115 CDD:409353 9/30 (30%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 1/7 (14%)
Ig strand F 108..115 CDD:409353 2/6 (33%)
CDR3 116..124 CDD:409353 0/38 (0%)
FR4 124..130 CDD:409353 3/16 (19%)
Ig strand G 124..130 CDD:409353 3/16 (19%)
Ig_3 134..208 CDD:404760 25/77 (32%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 2/3 (67%)
Ig strand E 187..191 CDD:409353 2/3 (67%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 23/102 (23%)
Ig strand C 256..260 CDD:409353 1/3 (33%)
Ig strand E 286..290 CDD:409353 0/3 (0%)
Ig strand F 300..305 CDD:409353 2/8 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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