DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kirrel2 and DIP-eta

DIOPT Version :9

Sequence 1:NP_766486.1 Gene:Kirrel2 / 243911 MGIID:2442334 Length:700 Species:Mus musculus
Sequence 2:NP_001188701.2 Gene:DIP-eta / 33793 FlyBaseID:FBgn0031725 Length:450 Species:Drosophila melanogaster


Alignment Length:388 Identity:93/388 - (23%)
Similarity:150/388 - (38%) Gaps:104/388 - (26%)


- Green bases have known domain annotations that are detailed below.


Mouse    21 PHFLQQPEDMVVLLGEEARLPCA---LGAYRGLVQW----TKDGLALGGERDLPGWSRYWISGNS 78
            |.|.....:|...:|.:|.|.|.   ||.|:  |.|    |:..|.:         ..:.|:.|.
  Fly    43 PKFSSPIVNMTAPVGRDAFLTCVVQDLGPYK--VAWLRVDTQTILTI---------QNHVITKNQ 96

Mouse    79 ----ASGQH---DLHIKPVELEDEASYECQASQAGLRSRPAQLHVMVPPEAPQVLGGP-SVSLVA 135
                |:.:|   .:.||.::..|:..|.||.:...::|:...|.|:|||:   :|..| |..:|.
  Fly    97 RIGIANSEHKTWTMRIKDIKESDKGWYMCQINTDPMKSQMGYLDVVVPPD---ILDYPTSTDMVV 158

Mouse   136 GVPGNLTCRSRGDSRPAPELLWFRD-GIRLDGSSFHQTTLKDKATG----TVENTLFLTPS--SH 193
            ....|:|.:......|.|.:.|.|: |:.:           :.|||    ::|.|..:.|:  .|
  Fly   159 REGSNVTLKCAATGSPEPTITWRRESGVPI-----------ELATGEEVMSIEGTDLVIPNVRRH 212

Mouse   194 DDGATLICRARSQALPTGRDTAVTLSLQYPPMVTLSAEPQTVQEGEKVTFLCQATAQPPVTGYRW 258
            ..||.| |.| |..:|......:||.:.:|||:|:..:.....||:.||..|::.|.|....| |
  Fly   213 HMGAYL-CIA-SNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINY-W 274

Mouse   259 AKGGSPVLGARGPRLEVVADATFLTEPVSCEVSNAVGSANRSTALEVLYGPILQAKPKSVSVDVG 323
            .:....::...|   :..|:.|            .:|....|..|.:  .|:.||          
  Fly   275 TRERGEIVPPGG---KYSANVT------------EIGGYRNSMRLHI--NPLTQA---------- 312

Mouse   324 KDASFSCVWRGNPLPRITWTRMGGSQVLSSGPT------LRLPSVALEDAGDYVCRAEPRRTG 380
            :..|:.||.:.                 |.|.|      .|:|    .:|.:||...|.|..|
  Fly   313 EFGSYRCVAKN-----------------SLGDTDGTIKLYRIP----PNAVNYVENFEARHKG 354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kirrel2NP_766486.1 IG 27..116 CDD:214652 24/102 (24%)
Ig 122..220 CDD:416386 27/105 (26%)
Ig strand A 123..126 CDD:409353 0/2 (0%)
Ig strand A' 129..133 CDD:409353 2/4 (50%)
Ig strand B 140..147 CDD:409353 2/6 (33%)
Cell attachment site. /evidence=ECO:0000255 146..148 0/1 (0%)
Ig strand C 153..158 CDD:409353 1/4 (25%)
Ig strand C' 161..163 CDD:409353 1/1 (100%)
Ig strand D 166..173 CDD:409353 0/6 (0%)
Ig strand E 180..188 CDD:409353 3/11 (27%)
Ig strand F 197..205 CDD:409353 4/7 (57%)
Ig strand G 211..217 CDD:409353 0/5 (0%)
Ig_3 223..292 CDD:404760 16/68 (24%)
Ig strand B 241..245 CDD:409353 2/3 (67%)
Ig strand C 255..259 CDD:409353 1/3 (33%)
Ig strand E 272..275 CDD:409353 0/2 (0%)
Ig strand F 281..290 CDD:409353 0/8 (0%)
Ig strand G 298..301 CDD:409353 0/2 (0%)
Ig 315..392 CDD:416386 14/72 (19%)
Ig strand A' 316..321 CDD:409353 0/4 (0%)
Ig strand B 324..333 CDD:409353 3/8 (38%)
Ig strand C 339..343 CDD:409353 0/3 (0%)
Ig strand C' 346..348 CDD:409353 0/1 (0%)
Ig strand D 351..354 CDD:409353 1/2 (50%)
Ig strand E 355..360 CDD:409353 2/10 (20%)
Ig strand F 368..376 CDD:409353 2/7 (29%)
Ig strand G 382..392 CDD:409353
Ig 394..498 CDD:416386
Ig strand A 395..399 CDD:409353
Ig strand A' 401..404 CDD:409353
Ig strand B 412..419 CDD:409353
Ig strand C 426..431 CDD:409353
Ig strand C' 433..436 CDD:409353
Ig strand D 444..451 CDD:409353
Ig strand E 461..468 CDD:409353
Ig strand F 479..486 CDD:409353
Ig strand G 489..496 CDD:409353
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..576
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 671..700
DIP-etaNP_001188701.2 Ig 51..141 CDD:299845 24/100 (24%)
IG_like 51..137 CDD:214653 23/96 (24%)
IG_like 153..237 CDD:214653 25/96 (26%)
Ig 161..224 CDD:299845 20/75 (27%)
IG_like 252..335 CDD:214653 24/127 (19%)
Ig 258..333 CDD:143165 22/119 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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