back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Kirrel2 and fipi

DIOPT Version :9

Sequence 1:	NP_766486.1	Gene:	Kirrel2 / 243911	MGIID:	2442334	Length:	700	Species:	Mus musculus
Sequence 2:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	494	Identity:	103/494 - (20%)
Similarity:	159/494 - (32%)	Gaps:	141/494 - (28%)

- Green bases have known domain annotations that are detailed below.

Mouse   162 IRLDGSSFHQTTLKDKATGTVENTLFLTPSSHD----DGATLICRARSQALPTGRDTAVTLSLQY 222
            :||.|...:...|...|......:|.|:|:.|.    ...:||.:.||.      |..|.|..:.
  Fly     1 MRLIGFILNLAALTAVAWANHHESLSLSPAEHSVVRYTNESLIVQCRSP------DPKVELHWKS 59

Mouse   223 PPMVTLSAE------PQTVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADATF 281
            |....:...      .||..|..|:.|...|.|.         ||.
  Fly    60 PKGEIIREHKGRIHIEQTSTEQLKIVFAHIALAD---------KGN------------------- 96

Mouse   282 LTEPVSCEVSNAVGSANRSTALEVLYGPILQAKPKSV-SVDVGKDASFSCVWRGNPLPRITWTRM 345
                .|||.::  ||.:..:...::|..|...:..:| :|..|:.|:..|..:|.|.|.:||...
  Fly    97 ----WSCEAAD--GSLHSKSFDLIVYQKITFTENATVMTVKEGEKATILCEVKGEPQPNVTWHFN 155

Mouse   346 GGSQVLSSGPT-----------LRLPSVALEDAGDYVCRA---------EPRRTGLGGGKAQARL 390
            |  |.:|:|..           |.:..|...|.|:|.|||         ...||.|  .|.:.:.
  Fly   156 G--QPISAGAADDSKFRILADGLLINKVTQNDTGEYACRAYQVNSIASDMQERTVL--MKIEHKP 216

Mouse   391 TVNAPPVVTALQPAPAFLRGPARLQCVVFASPAPDSVVWSWDEGFLEAGS-LGRFLVEAFPAPEV 454
            ..:..|.|:...   |::.|.|.|.|...|.| |.:..|......|.:.: |.....:::.:.
  Fly   217 IWSKTPFVSLKY---AYINGTATLMCEALAEP-PANFTWYRKHNKLHSNNRLYTIQSDSYWSS-- 275

Mouse   455 EGGQGPGLISVLHISGTQESDFTTGFNCSARNRLG--EGRVQIHLGRRDLLPTVRIVAGAASAAT 517
                     ..:|:..|...|   .:.|.|||.||  |...::..|.:...|....:.|..|...
  Fly   276 ---------LTIHVLNTSAFD---NYRCRARNDLGTIERTTRLEQGEKPPSPANFQLRGFNSNTF 328

Mouse   518 SLLMVITGVVLCCWRHGSLSKQKNLVRIPGSSEGSSSRGPEE--------------ETGSSEDRG 568
            .:::                              |:.|||.:              |.....|.|
  Fly   329 DVVL------------------------------SAPRGPPDSPMGVNGFRIEYMTEMEFKTDAG 363

Mouse   569 PIVHTDHSDLVLEEKEA-LETKDPTNGYYRVRGVSVSLS 606
            ...:....|...||... |.|....:..|.||..|.:|:
  Fly   364 KWTNARRKDYAFEEGATFLLTNLEPDTVYLVRAASRNLA 402

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.