DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kirrel2 and Fas2

DIOPT Version :9

Sequence 1:NP_766486.1 Gene:Kirrel2 / 243911 MGIID:2442334 Length:700 Species:Mus musculus
Sequence 2:NP_001284854.1 Gene:Fas2 / 31364 FlyBaseID:FBgn0000635 Length:885 Species:Drosophila melanogaster


Alignment Length:641 Identity:127/641 - (19%)
Similarity:211/641 - (32%) Gaps:217/641 - (33%)


- Green bases have known domain annotations that are detailed below.


Mouse    27 PEDMVVLLGEEARLPCALGA-YRGLVQWTKDGLALGGERDLPGWSRYWISGNSASGQHDLHIKPV 90
            ||:....||::..:.|.:.| ....:.|.::|..:....|     :|.:..|.      |.|:.|
  Fly   144 PENQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPIRTTND-----KYVVQTNG------LLIRNV 197

Mouse    91 ELEDEASYECQAS--QAG-LRSRPAQLHVMVPPEAPQVLGGP-SVSLVAGVPGNLTCRSRGDSRP 151
            :..||..|.|:|:  :.| |..|..::.|.:.||   ::..| ::..|.|.|....|.:||  :|
  Fly   198 QESDEGIYTCRAAVIETGELLERTIRVEVFIQPE---IISLPTNLEAVEGKPFAANCTARG--KP 257

Mouse   152 APELLWFRDGIRLDGSSFHQTTLKDKATGTVENTLFLTPSSHDDGATLICRARSQALPTGRDTAV 216
            .||:.|.||..:|:.::..:..:..: ||.|.    ::..|.||..|..|.|:::|....:.|.:
  Fly   258 VPEISWIRDATQLNVATADRFQVNPQ-TGLVT----ISSVSQDDYGTYTCLAKNRAGVVDQKTKL 317

Mouse   217 TLSLQYPPMVTLSAEPQTVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADATF 281
            .:                                                               
  Fly   318 NV--------------------------------------------------------------- 319

Mouse   282 LTEPVSCEVSNAVGSANRSTALEVLYGPILQAKPKSVSVDVGKDASFSCVWRGNPLPRITWTRMG 346
            |..|...|:.|..|                 |:.|.:::        :|..:|.|.|.||:.|.|
  Fly   320 LVRPQIYELYNVTG-----------------ARTKEIAI--------TCRAKGRPAPAITFRRWG 359

Mouse   347 GSQVLSSGP----------------------TLRLPSVALEDAGDYVCRAEPRRTGLGGGKAQAR 389
            ..:..::|.                      |||:.:....|.|.|.|.|  |..|....|. ..
  Fly   360 TQEEYTNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSDDGLYQCIA--RNKGADAYKT-GH 421

Mouse   390 LTVNAPPVVTALQPAP---AFLRGPARLQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPA 451
            :||...|..:.::..|   ::.:..|.|.|:....|.. ::.|.|:         ||.:.:.:..
  Fly   422 ITVEFAPDFSHMKELPPVFSWEQRKANLSCLAMGIPNA-TIEWHWN---------GRKIKDLYDT 476

Mouse   452 PEVEGGQGPGLISVLHISGTQESDFTTGFNCSARNRLGEGRVQIHLGRRDLLPTVRIVAGAASAA 516
            .....|.||....::|....|   :.:|:.|.|.|..|.....:.|....:...|.....:...|
  Fly   477 NLKIVGTGPRSDLIVHPVTRQ---YYSGYKCIATNIHGTAEHDMQLKEARVPDFVSEAKPSQLTA 538

Mouse   517 TSLLMVITGVVLCCWRHGSLSKQKNLVRIPGSSEGSSSRGPEEETGSSEDRGPIVHTDHSDLVLE 581
            |::...|                               |||..|.|.     ||:...     ::
  Fly   539 TTMTFDI-------------------------------RGPSTELGL-----PILAYS-----VQ 562

Mouse   582 EKEALETKDPTNGYYRVRGVSVSLSLGEAPGGGLFLPPPSPIGLPG--TPTYYDFK 635
            .|||| ..|.:..|.|      |.|            |.||..:.|  ..|.|.|:
  Fly   563 YKEAL-NPDWSTAYNR------SWS------------PDSPYIVEGLRPQTEYSFR 599

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kirrel2NP_766486.1 IG 27..116 CDD:214652 22/92 (24%)
Ig 122..220 CDD:416386 25/98 (26%)
Ig strand A 123..126 CDD:409353 0/2 (0%)
Ig strand A' 129..133 CDD:409353 1/4 (25%)
Ig strand B 140..147 CDD:409353 1/6 (17%)
Cell attachment site. /evidence=ECO:0000255 146..148 1/1 (100%)
Ig strand C 153..158 CDD:409353 2/4 (50%)
Ig strand C' 161..163 CDD:409353 0/1 (0%)
Ig strand D 166..173 CDD:409353 0/6 (0%)
Ig strand E 180..188 CDD:409353 2/7 (29%)
Ig strand F 197..205 CDD:409353 3/7 (43%)
Ig strand G 211..217 CDD:409353 1/5 (20%)
Ig_3 223..292 CDD:404760 3/68 (4%)
Ig strand B 241..245 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 0/3 (0%)
Ig strand E 272..275 CDD:409353 0/2 (0%)
Ig strand F 281..290 CDD:409353 2/8 (25%)
Ig strand G 298..301 CDD:409353 0/2 (0%)
Ig 315..392 CDD:416386 21/98 (21%)
Ig strand A' 316..321 CDD:409353 1/4 (25%)
Ig strand B 324..333 CDD:409353 1/8 (13%)
Ig strand C 339..343 CDD:409353 2/3 (67%)
Ig strand C' 346..348 CDD:409353 1/1 (100%)
Ig strand D 351..354 CDD:409353 0/2 (0%)
Ig strand E 355..360 CDD:409353 3/26 (12%)
Ig strand F 368..376 CDD:409353 4/7 (57%)
Ig strand G 382..392 CDD:409353 1/9 (11%)
Ig 394..498 CDD:416386 20/106 (19%)
Ig strand A 395..399 CDD:409353 1/3 (33%)
Ig strand A' 401..404 CDD:409353 0/2 (0%)
Ig strand B 412..419 CDD:409353 3/6 (50%)
Ig strand C 426..431 CDD:409353 1/4 (25%)
Ig strand C' 433..436 CDD:409353 0/2 (0%)
Ig strand D 444..451 CDD:409353 0/6 (0%)
Ig strand E 461..468 CDD:409353 0/6 (0%)
Ig strand F 479..486 CDD:409353 3/6 (50%)
Ig strand G 489..496 CDD:409353 1/6 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..576 7/33 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 671..700
Fas2NP_001284854.1 IG_like 39..133 CDD:214653
IG_like 144..226 CDD:214653 22/92 (24%)
IGc2 152..209 CDD:197706 15/67 (22%)
I-set 230..319 CDD:254352 27/98 (28%)
IGc2 243..309 CDD:197706 21/72 (29%)
IG_like 330..424 CDD:214653 24/121 (20%)
IGc2 339..412 CDD:197706 18/82 (22%)
Ig 447..518 CDD:143165 18/83 (22%)
fn3 534..611 CDD:278470 26/126 (21%)
FN3 640..735 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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