DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Styk1 and btl

DIOPT Version :9

Sequence 1:	NP_766479.1	Gene:	Styk1 / 243659	MGIID:	2141396	Length:	429	Species:	Mus musculus
Sequence 2:	NP_001014583.1	Gene:	btl / 39564	FlyBaseID:	FBgn0285896	Length:	1052	Species:	Drosophila melanogaster

Alignment Length:	464	Identity:	112/464 - (24%)
Similarity:	199/464 - (42%)	Gaps:	89/464 - (19%)

- Green bases have known domain annotations that are detailed below.

Mouse    40 GFLILLAIILWLFIRG--------QRSQRQS--------------------PGPRGTASVPASRG 76
            ||.:....|:.||:.|        :|.:|:.                    ||  |......|.|
  Fly   602 GFTLAAITIVALFLLGSAFITFMLRRLRREKLLKLRIETVHQWTKKVIIYRPG--GEEGSGCSSG 664

Mouse    77 RSQEAAGHGEKVLLPLKETS------VEGFLRAATPRLAKLQVPREQLLEVLEQIHSGSCGTL-- 133
            ..|......||....:..|.      .:||.....|..:..::||:||          |.|::
  Fly   665 DLQMPVIRIEKQRTTVSTTGTGGTDPAQGFNEYEFPLDSNWEIPRQQL----------SLGSILG 719

Mouse   134 ---YHATMTTKDHPKPKS-------VVLKALEDPVGLQEVQDFIGRIQFYQYLGKHKNLVQLEGC 188
               :...:..:....|:|       |.:|.:::.....::...:..::..:.:|||.|::.|.||
  Fly   720 EGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGC 784

Mouse   189 CTERLPLYMMLEDVVPGDLLSFLWTCRRDV----MTMDGLLYD--------LTEKQIYHIGKQIL 241
            |::..||::::|....|:|..||...|...    ...||.|.|        |.||::.....||.
  Fly   785 CSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIA 849

Mouse   242 LALEFLQEKHLFHGDVAARNILIQSDLTPKLCHLGLAYEVHAHGAISSARSSTIPLKWLAPERLL 306
            ..:|:|..:...|.|:||||:|:......|:...|||.::..........:..:|:||:|||.|.
  Fly   850 RGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQ 914

Mouse   307 LRPASIRGDIWSFGILLYEMVTLGAPPYPEV-PPTSILQYLQRKKIMKRPSSCSHAMYNIMKCCW 370
            .:....:.|:||:|:||:|::|.|..|||.: ....:..||...:.|::|:.||..:|.:|:.||
  Fly   915 EKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCW 979

Mouse   371 RWSEDSRPLLGQLLQR----LEAASRSADDKAV-LQVPELVVP------------ELYADVAGIR 418
            .:...:||...:|::.    |:.||.:.:|..: |.:|.|..|            |.:.:.:.:|
  Fly   980 HFESCARPTFAELVESFDGILQQASSNPNDAYLDLSMPMLETPPSSGDEDDGSDTETFRETSPLR 1044

Mouse   419 AESISYSFS 427
            .: .:|.|:
  Fly  1045 YQ-YTYKFN 1052

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Styk1	NP_766479.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	58..83		7/44 (16%)
Styk1	NP_766479.1	PKc_like	123..388	CDD:389743	76/293 (26%)
btl	NP_001014583.1	IG_like	149..232	CDD:214653
		IGc2	157..215	CDD:197706
		IG	247..336	CDD:214652
		Ig	258..340	CDD:143165
		I-set	394..479	CDD:254352
		IGc2	408..469	CDD:197706
		IG_like	492..583	CDD:214653
		Ig	507..583	CDD:299845
		PKc_like	700..1000	CDD:304357	81/309 (26%)
		TyrKc	712..996	CDD:197581	77/293 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810