Protein Alignment Cyp4b1 and Cyp4e1

DIOPT Version :9

• Sequence 1: NP_058695.2
• Gene: Cyp4b1 / 24307
• RGDID: 2480
• Length: 511
• Species: Rattus norvegicus
• Sequence 2: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Alignment Length: 545
• Identity: 169/545 - (31%)
• Similarity: 270/545 - (49%)
• Gaps: 78/545 - (14%)

  Rat    15 LWASVVILMVIVLKLFSL------LLRRQKLARAMDSFPGPPTHWLFGHALEIQKLGS-----LD 68
            :|  :|:...:.|.||.:      ||||:   |.::.|.||....|.|:|   .::|:     |:
  Fly     1 MW--IVLCAFLALPLFLVTYFELGLLRRK---RMLNKFQGPSMLPLVGNA---HQMGNTPTEILN 57

  Rat    69 KVVSWAQQFPHAH-PLWFGQFVGFLNIYEPDYAKAVYSRGD-PKAADVYDFFLQWIGKGLLVLDG 131
            :...|..::...: ..|.|.:...: :..|.|.:.:.|... ...:||||....|:|.|||...|
  Fly    58 RFFGWWHEYGKDNFRYWIGYYSNIM-VTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTG 121

  Rat   132 PKWFQHRKLLTPGFHYDVLKPYVAIFAESTRMMLDKWEKKASENKSFDIFCDVGHMALDTLMKCT 196
            .||.:|||::||.||:::|:.:..:..|::...:|:.:|.|.....||...:..::.||.:....
  Fly   122 SKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTA 186

  Rat   197 FGKGDSGLGHRDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLTPHGRRFLRACKIAHDHTDEVI 261
            .|...:.:.:|.:|...|..|:|..::.|..|....|.:::...|....:.:..|...|.|:|:|
  Fly   187 MGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEII 251

  Rat   262 RQ----RKAALQ-----DEKERKKIQQRRHLDFLDILLGVRDESGIKLSDAELRAEVDTFMFEGH 317
            .:    ||:.|:     ||..|||      :.|||.||..:.: |..|:..||..||.|||||||
  Fly   252 AKRIEVRKSGLEVGIKADEFSRKK------MAFLDTLLSSKVD-GRPLTSQELYEEVSTFMFEGH 309

  Rat   318 DTTTSGISWFLYCMALYPEHQQ-LCRE--EVRGI--LGDQDSFQWDDLAKMTYLTMCMKECFRLY 377
            ||||||:.:.:|.::.:|:.|: |..|  :|.|.  ||...:||  :::.|.:|.:.:||..|||
  Fly   310 DTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQ--EISTMKHLDLFIKEAQRLY 372

  Rat   378 PPVPQVYRQLNKPVTFVDGRSLPAGSLISLHIYALHRNSTVWPDPEVFDPLRFSPENAAGRHPFA 442
            |.||.:.|...|... :||..:|.|:.::|.:..|..|..|:.||..|.|.||..|...   ||.
  Fly   373 PSVPFIGRFTEKDYV-IDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKPG---PFE 433

  Rat   443 FMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFE------------------FSLDPSKM------ 483
            ::||||||||||||:||:.|:|.|.:..:..||                  ..|.|::.
  Fly   434 YVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAH 498

  Rat   484 -----PIKVPQLILRSKNGIHLYLK 503
                 ||....:.|:|:||:||.:|
  Fly   499 NHKYDPILSASMTLKSENGLHLRMK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4b1	NP_058695.2	p450	47..500	CDD:278495	155/502 (31%)
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	147/451 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348668
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650