Protein Alignment Cyp4b1 and Cyp4d8

DIOPT Version :9

• Sequence 1: NP_058695.2
• Gene: Cyp4b1 / 24307
• RGDID: 2480
• Length: 511
• Species: Rattus norvegicus
• Sequence 2: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 530
• Identity: 164/530 - (30%)
• Similarity: 271/530 - (51%)
• Gaps: 76/530 - (14%)

  Rat    20 VILMVIVLKLFSL--------LLRRQKLARAMDSFPGPPTHWLFGHALEIQ---------KLGSL 67
            ::|.::|:.||..        ..||:|:|    :.|||....|.| |:::.         |:|.
  Fly     1 MLLFLLVVLLFGAGWIIHLGQADRRRKVA----NLPGPICPPLIG-AMQLMLRLNPKTFIKVGR- 59

  Rat    68 DKVVSWAQQFPHAHPLWFGQFVGFLNIYEPDYAKAVYSRGDPKAAD-------------VYDFFL 119
                .:..:|.|...:|.             :.:.:...||.:..:             ||....
  Fly    60 ----EYVLKFGHLQRVWI-------------FNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLG 107

  Rat   120 QWIGKGLLVLDGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRMMLDKWEKKASENKSFDIFCDV 184
            ||:|.|||:.||..|.|.||::||.||:.:|:.:|.:|.:.:.:.:.:..:||:.| :||::..:
  Fly   108 QWLGNGLLLSDGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGN-TFDVYRSI 171

  Rat   185 GHMALDTLMKCTFGKGDSGLGHRDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLT-PHGR-RFL 247
            ...|||.:.:...|.......:....|..||::.|.|:..|..|.....:.::.|| ||.: |..
  Fly   172 CAAALDIIAETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQT 236

  Rat   248 RACKIAHDHTDEVIRQRKAALQDEKER------KKIQQRRHLDFLDILLGVRDESGIKLSDAELR 306
            :..:...:.|.:||.:|:.||:|::.:      :.:..:|.:..||:|| :....|..|::.|:|
  Fly   237 QLIRTMQEFTIKVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLL-MSTVDGRPLTNDEIR 300

  Rat   307 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQLCREEVRGILGDQDS--FQWDDLAKMTYLTMC 369
            .|||||||||||||||.:|:.|:.::.:||.|....||:..:||...|  ....||.::.|:...
  Fly   301 EEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECV 365

  Rat   370 MKECFRLYPPVPQVYRQLNKPVTFV-----DGRSLPAGSLISLHIYALHRNSTVWPDPEVFDPLR 429
            :||..|:|||||.|.|:|.....:.     || .:||||.|.:.|:.:||....:|:|:.|.|.|
  Fly   366 IKESLRMYPPVPIVGRKLQTDFKYTHSVHGDG-VIPAGSEIIIGIFGVHRQPETFPNPDEFIPER 429

  Rat   430 FSPENAAGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSLDPSKMPIK-VPQLILR 493
            .  ||.:...||..:||||||||||||:||..|||::.|. ::| |:.|.|....:: :..::||
  Fly   430 H--ENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAK-IVR-EYELLPMGQRVECIVNIVLR 490

  Rat   494 SKNGIHLYLK 503
            |:.|..|.::
  Fly   491 SETGFQLGMR 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4b1	NP_058695.2	p450	47..500	CDD:278495	155/490 (32%)
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	146/450 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348662
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750