Protein Alignment Cyp4b1 and Cyp6a19

DIOPT Version :9

• Sequence 1: NP_058695.2
• Gene: Cyp4b1 / 24307
• RGDID: 2480
• Length: 511
• Species: Rattus norvegicus
• Sequence 2: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 521
• Identity: 127/521 - (24%)
• Similarity: 207/521 - (39%)
• Gaps: 118/521 - (22%)

  Rat    64 LGSLDKVVSWAQQ---------FPHAHP---------LW--------------------FGQFVG 90
            :|.|..|..|..|         .||..|         ||                    .|.|.|
  Fly     9 VGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTYLKFRKQTDGPFAG 73

  Rat    91 F-------LNIYEPDYAKAVYSRGDPKAAD--VY----DFFLQWIGKGLLVLDGPKWFQHRKLLT 142
            |       :.|.:.|:.|.|..|...|..|  ||    |   ..:...|..::|.||...|:.||
  Fly    74 FYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKD---DPLTNNLATIEGQKWKNLRQKLT 135

  Rat   143 PGFHYDVLKP-YVAIFAESTRMMLDKWEKKASENKSFDIFCDVGHMALDTLMKCTFG-------- 198
            ..|....:|. :..:......|:....||.:|.:::.::...|.....|.:..|.||
  Fly   136 HTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVIGICAFGLKCNSLRD 200

  Rat   199 -------KGDSGLGHRDNSYYLAVSDLTLLMQQRID---SFQYHNDFIYWLTPHGRRFLRACKIA 253
                   .|.|.|..|.:.:.:   ||.:....::.   .||:       |.|..::|.  .||.
  Fly   201 PKAEFVQMGYSALRERRHGWLV---DLLIFGMPKLAVKLGFQF-------LLPSVQKFY--MKIV 253

  Rat   254 HDHTDEVIRQRKAALQDEKERKKIQQRRHLDFLDILLGVRD-------ESGIKLSDAELRAEVDT 311
            .|..            |.:.::|:.:.   ||:|.|:.::.       |:|:..:  |:.|:...
  Fly   254 QDTI------------DYRMKRKVTRN---DFMDTLIDMKQQYDKGDKENGLAFN--EVAAQAFV 301

  Rat   312 FMFEGHDTTTSGISWFLYCMALYPEHQQLCREEVRGILGDQD-SFQWDDLAKMTYLTMCMKECFR 375
            |...|.:..::.:.:.||.:|...:.|...|.|:..:|...: ..::|.:..:.|:...:.|..|
  Fly   302 FFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLR 366

  Rat   376 LYPPVPQVYRQLNKPVTFVDGR-SLPAGSLISLHIYALHRNSTVWPDPEVFDPLRFSPENAAGRH 439
            .:|.|..:.|...||....:.: .:.||:.:.:....:|.:...:|:||.|.|.||..|....|.
  Fly   367 KHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRP 431

  Rat   440 PFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLL--RFEFSLDP-SKMPIK--VPQLILRSKNGIH 499
            ..||:||.||||||||.:|  ..|:|:..|.||  .|.|.|.| :.:|:|  :..|:|.|:.|||
  Fly   432 TCAFLPFGAGPRNCIGLRF--GRMQVIIGLALLIHNFRFELHPKTPVPMKYTINNLLLGSEGGIH 494

  Rat   500 L 500
            |
  Fly   495 L 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4b1	NP_058695.2	p450	47..500	CDD:278495	125/519 (24%)
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	120/496 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900