Protein Alignment Cyp4b1 and Cyp4d1

DIOPT Version :10

• Sequence 1: NP_058695.2
• Gene: Cyp4b1 / 24307
• RGDID: 2480
• Length: 511
• Species: Rattus norvegicus
• Sequence 2: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 524
• Identity: 165/524 - (31%)
• Similarity: 268/524 - (51%)
• Gaps: 73/524 - (13%)

  Rat    19 VVILMVIVLKLF-SLLLRRQKLARAMD---SFPGPPTHWLFGHA---------------LEIQKL 64
            :||..::...|| .|||...|..|.:|   ..||||...|.||.               .|..:.
  Fly     3 LVIGAILASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMET 67

  Rat    65 GSLDKVVSWAQQFPHAHPLWFGQFVGFLNIYEPDYAKAVYSRGDPKAADV-------------YD 116
            .|.|:|:.          :|.|..:..|             .|:||..:|             |.
  Fly    68 YSKDQVLK----------VWLGPELNVL-------------MGNPKDVEVVLGTLRFNDKAGEYK 109

  Rat   117 FFLQWIGKGLLVLDGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRMMLDKWEKKASE--NKSFD 179
            ....|:.:||||..|.||.:.||::||.||:.:|..:|.:|.:.:|.:|...|:...:  :..|.
  Fly   110 ALEPWLKEGLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFS 174

  Rat   180 IFCDVGHMALDTLMKCTFGKGDSGLGHRDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLTPHGR 244
            ::..:....:||:.:...|...:...:.|:.|..||..:::::.:|:.:..|..|..|.|||..|
  Fly   175 LYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLAR 239

  Rat   245 RFLRACKIAHDHTDEVIRQRKAAL-------QDEKERKKIQQRRHLDFLDILL-GVRDESGIKLS 301
            ...:|..:.|..|:::|.||:..|       :...:...:..:|.:.|||||| ...||.  .||
  Fly   240 AEKKALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDER--PLS 302

  Rat   302 DAELRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQLCREEVRGILGDQDS--FQWDDLAKMT 364
            :.::|.|||||||||||||:|.:.:|.|.:|.:||.|:.|.||:|.::|:..|  ..::.|.::.
  Fly   303 NLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLH 367

  Rat   365 YLTMCMKECFRLYPPVPQVYRQLNKPVTFVDGRSLPAGSLISLHIYALHRNSTVWPDPEVFDPLR 429
            |:.:|:||..|:||.||.:.|::.:... ::|:.:|||:.|.:....|.|...::.:|.:|.|.|
  Fly   368 YVDLCVKETLRMYPSVPLLGRKVLEDCE-INGKLIPAGTNIGISPLYLGRREELFSEPNIFKPER 431

  Rat   430 FSPENAAGR-HPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFE--FSLDPSKMPIKVPQLI 491
            |.....|.: :|:|::||||||||||||:|||.|:|.:.|..|..:|  |..|.|:.|:.:.:||
  Fly   432 FDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELI 496

  Rat   492 LRSK 495
            ||:|
  Fly   497 LRTK 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4b1	NP_058695.2	CYP4B-like	67..501	CDD:410771	146/457 (32%)
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	145/454 (32%)