Protein Alignment Cyp4a2 and Cyp4c3

DIOPT Version :9

• Sequence 1: XP_038965182.1
• Gene: Cyp4a2 / 24306
• RGDID: 2479
• Length: 517
• Species: Rattus norvegicus
• Sequence 2: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 541
• Identity: 178/541 - (32%)
• Similarity: 283/541 - (52%)
• Gaps: 64/541 - (11%)

  Rat     4 SVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLK--- 65
            |.:||      ::.|..|:.|  :|||::..     ||..|:|.:||.|...:....|:.::
  Fly    24 SGYSP------ITVFLLGSIL--IFLVVYNK-----RRSRLVKYIEKIPGPAAMPFLGNAIEMNV 75

  Rat    66 --DREFQQVL----TWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGR----SDPKPYQSLAPW 120
              |..|.:|:    .|..:. |....| .|:..||||::|:.|:.:|..    :....|..|.||
  Fly    76 DHDELFNRVIGMQKLWGTRI-GINRVW-QGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHPW 138

  Rat   121 IGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSL 185
            :|.|||....:||...|::||||||:.||..::.:..:..:::..|. .::.......:|.||:|
  Fly   139 LGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKL-AVEVGSEAFNLFPYVTL 202

  Rat   186 MTLDTVMKCAFSHQGSVQLDVNSRS-YTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRA 249
            .|||.|.:.|...:  :....||.| |.|||..:.:::..|....:..:..|::::::.:|
  Fly   203 CTLDIVCETAMGRR--IYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKL---- 261

  Rat   250 CQIAHEHTGSVFLLPAFLSLSDGVIKTRKAQLQNEEE------------LQKARKKRHLDFLDIL 302
                  |...:..|..|   |:.||:.|||:|...:|            .....||:.|.|||:|
  Fly   262 ------HQSYINTLHGF---SNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLL 317

  Rat   303 LFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDG-- 365
            :.|..| |..||:||:|.|||||||||||||::.|||..:.|..|||:|||..||:.||.||.
  Fly   318 IDASKE-GTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKE 381

  Rat   366 TSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPS 430
            |..|..:|..|.|...|||::|||:..||.::|.:...|.. .|:.:|.|.:..|:.|.||.||.
  Fly   382 TPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNI-GGKIVPAGTQAIIMTYALHRNPR 445

  Rat   431 YWPNPKVFDPSRFSPD--SPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTR 493
            .:|.|:.|:|..|.|:  :.||..||:|||.|.|||||::||:.|.|..::..|.::::.....|
  Fly   446 VFPKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRR 510

  Rat   494 IPVP-MPRLVLKSKNGIHLRL 513
            ..:. :..|:|:.|:|:.:::
  Fly   511 EDLTLLGELILRPKDGLRVKI 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a2	XP_038965182.1	CYP4B-like	69..512	CDD:410771	160/468 (34%)
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	163/491 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348410
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650