Protein Alignment Cyp4a2 and Cyp313a3

DIOPT Version :10

• Sequence 1: NP_001038235.1
• Gene: Cyp4a2 / 24306
• RGDID: 2479
• Length: 504
• Species: Rattus norvegicus
• Sequence 2: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Alignment Length: 496
• Identity: 128/496 - (25%)
• Similarity: 198/496 - (39%)
• Gaps: 100/496 - (20%)

  Rat    29 LVLFKAVQFYLRRQWLLKALE----KFPSTPSHWLWGHNLKDREFQQVLTWVEK----------F 79
            |:|...|.|::...|..:.|.    |.|..     .|..:....|:.::|:..|          :
  Fly     6 LLLAVGVCFWIYFLWSRRRLYMMHFKIPGP-----MGLPILGIAFEYLITYKRKMSIRTKYMDIY 65

  Rat    80 PGACLQWLSGSTARVLLYDPDYVKVV------LGRSD--PKPYQSLAPWIGYGLLLLNGKKWFQH 136
            ...||.|: |.|..|:..||...:.:      |.||.  .||..|..   |.|||.|...||...
  Fly    66 GSTCLVWV-GPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCT---GDGLLSLEASKWVDR 126

  Rat   137 RRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAF--SHQ 199
            |:.|.|||..::|..::.|.......::...:.|..|...         ...|.:::.:|  :.|
  Fly   127 RKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEK---------KVRDDIVRWSFRIATQ 182

  Rat   200 GSVQLDV------NSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTD 258
            .:|..||      .:.|..|:.|....:|...|...|..|.|.                   .|.
  Fly   183 TTVGTDVKKDASFKNDSVLKSYETFMKIIVMNVLLPFTHNKIF-------------------STL 228

  Rat   259 GVIKTRKAQLQNEEELQKARKKRHL-DFLDILLFAKMEDGK------------------SLSDED 304
            |..:|:||       |.|:...:.: ..:|..|..|.|.|.                  .:|.|:
  Fly   229 GGFETQKA-------LAKSNVNKMIGTIVDKKLMTKPESGSQPEITSVINKAIELHRNGEMSREE 286

  Rat   305 LRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQS---ILGDGTSVTWDHLDQMPYT 366
            :::|..:|:....:||...:......||..||||:...:|::.   :.|| ..||:|.|.:|.:.
  Fly   287 VQSECCSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGD-FEVTYDDLQRMVFL 350

  Rat   367 TMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYW-PNPKVFDPSRF 430
            ...:.|.|||...||...||.........|..||||:.:.|.|:..|.|..:| .:|..|:|..|
  Fly   351 ERVVNETLRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHF 415

  Rat   431 SPDS--PRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTL 469
            .||:  .||.:||:|||.|.|||||.::.:...|:|::..|
  Fly   416 LPDNVRDRHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKIL 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a2	NP_001038235.1	CYP4B-like	69..499	CDD:410771	119/452 (26%)
Cyp313a3	NP_650170.2	CYP313-like	66..487	CDD:410680	116/431 (27%)