Protein Alignment Cyp4a2 and Cyp4p3

DIOPT Version :10

• Sequence 1: NP_001038235.1
• Gene: Cyp4a2 / 24306
• RGDID: 2479
• Length: 504
• Species: Rattus norvegicus
• Sequence 2: NP_610473.1
• Gene: Cyp4p3 / 35948
• FlyBaseID: FBgn0033397
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 529
• Identity: 151/529 - (28%)
• Similarity: 262/529 - (49%)
• Gaps: 73/529 - (13%)

  Rat    23 FLLSLFLVLFKAVQFYLRRQW-----------------------LLKALEKFPSTPSHWLWGHNL 64
            :|:..|:||.:.: :.|.|.:                       |:|....|.:  |..|:|
  Fly     5 WLVGAFIVLIQWI-YRLNRDYCILGFFAKRIRTKNGQNPESIAPLVKGSTIFAN--SFDLYG--- 63

  Rat    65 KDRE--FQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPK------PYQSLAPWI 121
            ||..  |:......:|...:..::..| ||...:.|.|..:.||  :||.      .|..|.|::
  Fly    64 KDHSGVFEHSRDCAKKLGKSYAEYAMG-TAIYNVIDADSAERVL--NDPNLINKGTIYDFLHPFL 125

  Rat   122 GYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLM 186
            ..|||...||||...|:||:|.||::||..:.:|........|::::..|:.  .:.:...:...
  Fly   126 RTGLLTSTGKKWHARRKMLSPTFHFNILNQFQEIFITESLKFLEQFKGNDEA--IISLNEVIPRF 188

  Rat   187 TLDTVMKCAFSHQGSVQLDVNSRS---YTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRR 248
            ||:::.:.|.    .|:||..:..   |.:....:......|:.:....:..::.|.::...: .
  Fly   189 TLNSICETAM----GVKLDEMAEKGDRYRENFRQIEECFIRRMSNPLLWSDTLFKMFAEKDYA-S 248

  Rat   249 ACQIAHEHTDGVIKTRKAQLQN-----------EEELQKARKKRHLDFLDILLFAKMEDGKSLSD 302
            |..:.|..:..:|..|:.||.:           |:||..::|:  ...||.|:.|: :||  |.|
  Fly   249 ALDVVHGFSSEIIAKRRDQLNDEIDSRGNTQTAEDELFTSKKR--FAMLDTLILAE-KDG--LID 308

  Rat   303 E-DLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSV-TWDHLDQMPY 365
            . .:..||||.||||:|||:.|:.:....::.:||.||:|.:|:|:.:.|..:: ....|:::..
  Fly   309 HIGICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQANIDDELNILNIGQLNKLKN 373

  Rat   366 TTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRF 430
            ....|||.:||:..||::.||.:......:|..:|||.::.:.::.:|.||.||.:|:.|.|.||
  Fly   374 LEYFIKETMRLFPSVPAMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYWDSPEEFRPERF 438

  Rat   431 SPDSP--RHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLP--DPTRIPVPMPRLVLK 491
            .|::.  ||::||:|||.|.|||||::|||.|:|..:...|.:|::||  ||..| |....|.|:
  Fly   439 LPENSQNRHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTI-VFQTGLTLR 502

  Rat   492 SKNGIHLRL 500
            :||.||::|
  Fly   503 TKNQIHVKL 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a2	NP_001038235.1	CYP4B-like	69..499	CDD:410771	136/455 (30%)
Cyp4p3	NP_610473.1	CYP4	81..509	CDD:410721	133/443 (30%)