Protein Alignment Cyp4a2 and Cyp4e2

DIOPT Version :9

• Sequence 1: XP_038965182.1
• Gene: Cyp4a2 / 24306
• RGDID: 2479
• Length: 517
• Species: Rattus norvegicus
• Sequence 2: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 563
• Identity: 162/563 - (28%)
• Similarity: 258/563 - (45%)
• Gaps: 111/563 - (19%)

  Rat    23 FLLSLFLVLFKAVQFYL-----RRQWLLKALEKF---------------PSTPSHWL-----WGH 62
            |:|.:||.|...:..||     ||:   :.|.||               ...||..|     |.|
  Fly     3 FVLYIFLALPLLLVAYLELSTFRRR---RVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWWH 64

  Rat    63 NLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLG------RSDPKPYQSLAPWI 121
            ......|   :.|:            |:.:.||:....|::.:|.      :||  .||...||:
  Fly    65 QYGKDNF---VFWI------------GTYSNVLVTSSKYLEFILSSQTLITKSD--IYQLTHPWL 112

  Rat   122 GYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIF------ 180
            |.|||...|.||.:||:|:|||||::||:.:.::|.::.:..:...:.:...|:   ||
  Fly   113 GLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDN---IFDFQEQA 174

  Rat   181 HYVSL-MTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGR 244
            ||::| :..||.|..:.:     .::..|.|..:|.:|:...|..|.......|.::|.::.|..
  Fly   175 HYLTLDVICDTAMGVSIN-----AMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYP 234

  Rat   245 LSRRACQIAHEHTGSVFLLPAFLSLSDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMED 309
            ...|..:...:.|..: :.....:...|.:.|....       :..|||  :.|||.||.:.: |
  Fly   235 AYSRTLKTLQDFTNEI-IAKRIEAHKSGAVSTNAGD-------EFTRKK--MAFLDTLLSSTI-D 288

  Rat   310 GKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGD---GTSVTWD 371
            |:.|:.::|..||.||||||||||.||:|:..|.|:.|.:.|.:..:|.:.::|:   |...|:.
  Fly   289 GRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQ 353

  Rat   372 HLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPK 436
            .:.||.|..:.||||.|:|..||.:.|........ ||..:|||..:.:.:..|.:|...:.:|.
  Fly   354 EISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVI-DGDLVPKGTTLNLGLVMLGYNEKVFKDPH 417

  Rat   437 VFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLP------------ 489
            .|.|.||..:.| ....|:|||.|.|||||::||:.|:|..|:..:..||:||
  Fly   418 KFRPERFELEKP-GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYI 481

  Rat   490 --------------DPTR---IPVPMPRLVLKSKNGIHLRLKK 515
                          ||.|   .|:....|.|||:||:::|||:
  Fly   482 STTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKE 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a2	XP_038965182.1	CYP4B-like	69..512	CDD:410771	142/487 (29%)
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	135/471 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348481
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650