Protein Alignment Cyp21a1 and spo

DIOPT Version :9

• Sequence 1: NP_476442.2
• Gene: Cyp21a1 / 24298
• RGDID: 2461
• Length: 493
• Species: Rattus norvegicus
• Sequence 2: NP_001286943.1
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 515
• Identity: 129/515 - (25%)
• Similarity: 210/515 - (40%)
• Gaps: 124/515 - (24%)

  Rat    38 GFLHFLQ--PNLPVYLF-GLAQKLGPIYRIRLGLQDVVVLNSNKTIEEALIQKWVDFAGRP---- 95
            |.||.|.  .:.|...| .|||:.|.||.:..|....:|:|:.:.|.|.|.|.....:|||
  Fly    65 GNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIR 129

  Rat    96 --QILDGKMNFDLSMGDYSLTWKAHKKLSR-------------------------------SALV 127
              ::..|:.:..|::.|:|...:..:.|:|                               :.||
  Fly   130 YHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHWNRELGNQLV 194

  Rat   128 LGMRDSMEPLVEQLTQEFCERMRAQAGASVAIHKEFSLLTCSIISCLTFGDKQDSTLLNATHSCV 192
            .|...:::||:    .:.|..|             ||...||    |.| |..|...
  Fly   195 PGEPINIKPLI----LKACANM-------------FSQYMCS----LRF-DYDDVDF-------- 229

  Rat   193 RDLLKAWNH--WSV---QILDIIPFLRFFPNPGLWKLKQFQESRDHIVMQELKRHKDSLV--AGQ 250
            :.:::.::.  |.:   ..||.:|:|..|....|.|:..:..:....:|:.:.||::..|  ...
  Fly   230 QQIVQYFDEIFWEINQGHPLDFLPWLYPFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEP 294

  Rat   251 WKDMIDYMLQGVEKQRDARDPGQLHERHVHMSVVDLFVGGTETTAATLSWAVAFLLHHPEIQKRL 315
            .:|..|.:|:.:.:.:|.       .|:..:.:::.|:||.......:...:|::..:.:|.:|:
  Fly   295 DRDFTDALLKSLLEDKDV-------SRNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRI 352

  Rat   316 QEELDLKLAP---SSQLLYKNRMQLPLLMATIAEVLRL--RPVVPMALPHRATKASSISGYDIPK 375
            |||:|..:..   |..||..|.|  |..||||.||||.  .|:|    ||.||:.:.||||.:.|
  Fly   353 QEEIDAIIEEENRSINLLDMNAM--PYTMATIFEVLRYSSSPIV----PHVATEDTVISGYGVTK 411

  Rat   376 DTIIIPNIQGANLDEMVWELPSKFWPDRFLESGK--SPR---------------------IP--- 414
            .||:..|....|..|..|..|.:|.|.||||..|  ||:                     ||
  Fly   412 GTIVFINNYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFL 476

  Rat   415 TFGCGARVCLGEPLARLELFVVLARLLQTFTLLPPPDGTL---PSLQPLPYTGINLLIPP 471
            .|..|.|.|:|:.|.|...|:|:..::|.:.:......|:   |....||.....|::.|
  Fly   477 PFSIGKRTCIGQNLVRGFGFLVVVNVMQRYNISSHNPSTIKISPESLALPADCFPLVLTP 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp21a1	NP_476442.2	p450	31..474	CDD:278495	129/515 (25%)
		Steroid-binding. /evidence=ECO:0000250	337..353		9/17 (53%)
spo	NP_001286943.1	p450	56..540	CDD:299894	129/515 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000