Protein Alignment Cyp11b2 and Cyp12a4

DIOPT Version :9

• Sequence 1: NP_036670.2
• Gene: Cyp11b2 / 24294
• RGDID: 2454
• Length: 502
• Species: Rattus norvegicus
• Sequence 2: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 511
• Identity: 138/511 - (27%)
• Similarity: 234/511 - (45%)
• Gaps: 76/511 - (14%)

  Rat    38 KPFEAIPQYSRNKWLKMIQILREQGQ-ENLHL-EMHQAF-QELGPIFRHSA--GGAQIVSVMLPE 97
            ||||.||:.  |.|...:::....|: :|:.| ||.:|. |:.|.||....  |....:|...|:
  Fly    45 KPFEQIPRL--NMWALSMKMSMPGGKYKNMELMEMFEAMRQDYGDIFFMPGIMGNPPFLSTHNPQ 107

  Rat    98 DAEKLHQVESILPRRMHLEPWVAHRE------LRGLRRGVFLLNGADWRFNRLKLNPNVLSPKAV 156
            |.|.:.:.|.:.|.|......:.|||      .:|: .||....|..|...|..:||.::.||.|
  Fly   108 DFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGV-MGVIPTQGKPWGDFRTVVNPVLMQPKNV 171

  Rat   157 QNFVPMVDEVARDFLEALKKKVRQNARGSLTMDVQQSLFNYTIEASNFALFGERLGLL-GHDLNP 220
            :.:...:.:|.::|::.: .::|.........|...::..:|:|:.:.....::|||| ..:...
  Fly   172 RLYYKKMSQVNQEFVQRI-LELRDPDTLEAPDDFIDTINRWTLESVSVVALDKQLGLLKNSNKES 235

  Rat   221 GSLKFIHALHSMFKSTTQLLFLPRSLTRWTSTRVWKEHFDAWDVISE----YANRCIWKVHQELR 281
            .:||..|.|...|..:..|...| |..|:..|...|....|.|.|.|    |.:..|.::.:|.:
  Fly   236 EALKLFHYLDEFFIVSIDLEMKP-SPWRYIKTPKLKRLMRALDGIQEVTLAYVDEAIERLDKEAK 299

  Rat   282 LGSSQTYSGIV----AALITQGALPLDAIKAN--SMELTAGSVDTTAIPLVMTLFELARNPDVQQ 340
                   .|:|    ...:.:..|.:|...|.  :|::....||||:......|..||:||:.|.
  Fly   300 -------EGVVRPENEQSVLEKLLKVDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQA 357

  Rat   341 ALRQETLAAEASIAAN-----PQKAMSDLPLLRAALKETLRLYP--VGGFLERILNSDLVLQNYH 398
            .||:|.:    .:..|     .:.:|.::|.|||.:||:.||:|  ||.  .|:|..|.||..|.
  Fly   358 RLREEVM----KVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGN--ARVLARDAVLSGYR 416

  Rat   399 VPAGTLV-LLYLYSMGRNPAVFPRPERYMPQRWLERKRS---------------FQHLAFGFGVR 447
            |||||.| ::.|.::.|: ..||:...::|:|||...:.               |..|.||||.|
  Fly   417 VPAGTYVNIVPLNALTRD-EYFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPR 480

  Rat   448 QCLGRRLAEVEMLLLLHHMLKTFQVE------------TLRQEDVQMAYRFVLMPS 491
            .|:|:|:.|:|:.|....:::.|.||            .:...::.:.::|:.:|:
  Fly   481 MCVGKRIVEMELELGTARLIRNFNVEFNYPTENAFRSALINLPNIPLKFKFIDLPN 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp11b2	NP_036670.2	p450	44..498	CDD:278495	133/505 (26%)
Cyp12a4	NP_650783.2	p450	72..531	CDD:299894	126/475 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820