Protein Alignment Cyp11b2 and shd

DIOPT Version :10

• Sequence 1: NP_036670.2
• Gene: Cyp11b2 / 24294
• RGDID: 2454
• Length: 502
• Species: Rattus norvegicus
• Sequence 2: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Alignment Length: 507
• Identity: 123/507 - (24%)
• Similarity: 212/507 - (41%)
• Gaps: 90/507 - (17%)

  Rat    34 PKTLKPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQAFQELGP-----IFRHSAGGAQIVSV 93
            ||.: ||..      .||:.::...|.:     ..::|:.:.:|..     :.........||.:
  Fly    65 PKRI-PFLG------TKWIFLLFFRRYK-----MTKLHEVYADLNRQYGDIVLEVMPSNVPIVHL 117

  Rat    94 MLPEDAEKLHQVESILPRRMHLEPWVAHRELRGLRR---GVFLLNGADWRFNRLKLNPNVLSPKA 155
            ...:|.||:.:..|..|.|...|..|.:|:.|..|.   |:....|..|:..|..|..::.||:.
  Fly   118 YNRDDLEKVLKYPSKYPFRPPTEIIVMYRQSRPDRYASVGIVNEQGPMWQRLRSSLTSSITSPRV 182

  Rat   156 VQNFVPMVDEVARDFLEALKKKVRQNARGSLTMDVQ--QSLFNYT-IEASNFALFGERLGLLGHD 217
            :|||:|.::.|..||:|.|:.:     |...|:.|.  :.|.|.. :||....:.|.|:|.|..|
  Fly   183 LQNFLPALNAVCDDFIELLRAR-----RDPDTLVVPNFEELANLMGLEAVCTLMLGRRMGFLAID 242

  Rat   218 L-NPGSLKFIHALHSMFKSTTQLLFLPR-------SLTRWTSTRVWKEHFDA----WDVISEYAN 270
            . .|..:       |...:..:.||:.:       .|.::..|:.:::...|    :|||||..:
  Fly   243 TKQPQKI-------SQLAAAVKQLFISQRDSYYGLGLWKYFPTKTYRDFARAEDLIYDVISEIID 300

  Rat   271 RCIWKVHQELRLGSSQTYSGIVAALITQGALPLDAIKANSMEL---------------TAGSVDT 320
                  |:...|..|       ||.....|..|.:|..|.:||               .|..::|
  Fly   301 ------HELEELKKS-------AACEDDEAAGLRSIFLNILELKDLDIRDKKSAIIDFIAAGIET 352

  Rat   321 TAIPLVMTLFELARNPDVQQALRQETLA-AEASIAANPQKAMSDLPLLRAALKETLRLYPVGGFL 384
            .|..|:..|..:..:|.....:..|... .:.:|.   |.|:::....:|.::|:.||.|....|
  Fly   353 LANTLLFVLSSVTGDPGAMPRILSEFCEYRDTNIL---QDALTNATYTKACIQESYRLRPTAFCL 414

  Rat   385 ERILNSDLVLQNYHVPAGTLVLLYLYSMGRNPAVFPRPERYMPQRWLE-RKRSFQ--------HL 440
            .|||..|:.|..|.:.|||:||..........:.|...:::.|:||:: ...:|.        .:
  Fly   415 ARILEEDMELSGYSLNAGTVVLCQNMIACHKDSNFQGAKQFTPERWIDPATENFTVNVDNASIVV 479

  Rat   441 AFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQVETLRQEDVQMAYRFVLMPSS 492
            .||.|.|.|.|:|..|:|::|||..|:..|.|..::  .::..:.|:|.|.:
  Fly   480 PFGVGRRSCPGKRFVEMEVVLLLAKMVLAFDVSFVK--PLETEFEFLLAPKT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp11b2	NP_036670.2	cytochrome_P450	74..498	CDD:477761	115/467 (25%)
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	114/462 (25%)